Sequential Versus Single O2 Levels on Human Embryo Development

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Clinical Trial Summary

Myriads of elements affect human embryo culture in vitro. These include, but not limited to, air quality, culture media, culture temperature, incubator humidity, pH, and O2 levels. O2 tension has been thoroughly investigated and, to date, 5% O2 level is superior to 20%. Reports showed that lowering the O2 from Day 3 of embryo culture seems to be physiological.

See also
Status	Clinical Trial	Phase
Completed	`NCT03964805` - Oxygen Tension on Human Embryonic Development	N/A
Recruiting	`NCT03464643` - A Prospective Study Comparing the Outcomes of Single Versus Group Culture in Preimplantation Genetic Testing Cycles	N/A
Completed	`NCT01706900` - Incubator Temperature for Culturing Human Embryos	N/A
Completed	`NCT01904006` - Impact of Human Embryo Culture System on Live Birth	N/A

NCT number	NCT03630900
Study type	Interventional
Source	Ibn Sina Hospital
Contact
Status	Completed
Phase	N/A
Start date	August 24, 2018
Completion date	July 1, 2019

Sequential Versus Single O2 Levels on Human Embryo Development

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms