Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine if abuse liability indices will be impacted by varying flavors and e-cigarette (ECIG) nicotine delivery capability (i.e., nicotine flux) among current combustible cigarette users. The investigators will compare abuse liability indices between three FDA-authorized ECIG products that vary in nicotine flux (but are all tobacco flavor) and own brand cigarettes. The investigators will also test the influence of ECIG flavor availability (tobacco vs. menthol) within three ECIG product classes.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05971823
Study type Interventional
Source Virginia Commonwealth University
Contact Caroline O Cobb, PhD
Phone 804-827-3562
Email cobbco@vcu.edu
Status Recruiting
Phase N/A
Start date July 31, 2023
Completion date August 1, 2024

See also
  Status Clinical Trial Phase
Completed NCT04123041 - Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems N/A
Completed NCT04107779 - Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to JUUL ENDS N/A
Completed NCT04620616 - Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by ENDS Consumers N/A
Recruiting NCT05306158 - Dual Use Approach Bias Training for Nicotine Addiction N/A
Completed NCT04143256 - Evaluating Selected Constituents in the Exhaled Breath Samples N/A
Completed NCT04088175 - Study to Characterize Puffing Topography With Use of JUUL Electronic Nicotine Delivery Systems (ENDS) in Adult, Closed-System ENDS Consumers N/A
Completed NCT04708106 - Characterization of Product Use in Smokers Switching From Cigarettes to a RELX Electronic Nicotine Delivery System N/A
Recruiting NCT06291597 - Vaping Adverse Lung and Heart Events Cohort
Completed NCT05134415 - Use Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS Consumers N/A
Completed NCT04640285 - Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers N/A
Recruiting NCT05316727 - Electronic Nicotine Delivery Devices and Potential Progression to Acute Lung Injury
Completed NCT04192032 - Assessing the Effect of Flavor on ENDS Users' Experiences and Exposures N/A
Recruiting NCT05278065 - E-cigarettes for Harm Reduction in Adults With Asthma N/A
Recruiting NCT05206435 - Methadone-Maintained Smokers Switching to E-Cigarettes Phase 4
Completed NCT04316234 - Acute Health Effects of Passive Vape Among COPD Patients N/A
Completed NCT04450537 - PACE Vape Messaging Study N/A
Recruiting NCT05338801 - Effect of Menthol on ENDS Users' Addiction and Exposure N/A
Recruiting NCT05423340 - Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems N/A
Terminated NCT03974152 - Effects of Nicotine Salt Aerosol on Cigarette Smokers N/A
Not yet recruiting NCT06063421 - Comparison of Nicotine Replacement Therapy and Electronic Cigarettes for Smoking Cessation in Pakistan N/A