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General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia

Electroencephalogram Clinical Trial

Official title:
General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia

Clinical Trial Summary

The change profiles of indices derived from pEEG such as phase-amplitude coupling and bicoherence based on individual general anesthetics in children have not been examined in previous literature. Whether those indices have the abilities to predict individual drug-related anesthesia depth in children need to be explored.

Clinical Trial Description

The need to maintain a proper depth of general anesthesia during pediatric surgery is an important aspect of anesthesiology. An inappropriate anesthesia depth increases the risk of intraoperative awareness or delay in recovery in children undergoing surgery. Current modalities for anesthesia depth monitoring showed limited accuracy in children. The electroencephalogram (EEG) can be analyzed in its raw form for characteristic drug-induced patterns of change or summarized using mathematical parameters as a processed electroencephalogram (pEEG). The change profiles of indices derived from pEEG such as phase-amplitude coupling and bicoherence based on individual general anesthetics in children have not been examined in previous literature. Whether those indices have the abilities to predict individual drug-related anesthesia depth in children need to be explored. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05210764
Study type Observational
Source Peking University First Hospital
Contact Linlin Song, MD
Phone 86-13501309217
Email songlinlinlynkia@163.com
Status Recruiting
Phase
Start date June 1, 2022
Completion date August 1, 2026
View Details
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