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Elective Surgical Procedure clinical trials

View clinical trials related to Elective Surgical Procedure.

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NCT ID: NCT04884698 Completed - Healthy Subjects Clinical Trials

"Electromagnetical Stimulation of Phrenic Nerve to Generate Contraction of the Diaphragm"

Start date: June 25, 2021
Phase: N/A
Study type: Interventional

The scientific study is intended to show that external non-invasive electromagnetic stimulation can be used to safely and effectively stimulate the phrenic nerve in awake healthy subjects as well as in ventilated, anesthetized patients and that the stimulation can generate a diaphragmatic contraction that generates significant breath volume - a Controlled Own Breath (COB). Also of interest is the reproducibility of the generated diaphragmatic movements and the reliability of different feedback signals for detecting the generated diaphragmatic contraction. This applies to inspiration and expiration detection for subsequent synchronization mechanisms of the magnetic stimulator for patient-initiated breathing as well as to contraction intensity. Further, the characterization of the position finding process is of great importance, so that technical developments can further simplify the process of coil positioning in the future. The possible occurrence of discomfort and pain sensation will also be investigated in awake healthy volunteers. Different stimulation protocols will be used. Finally, it will be investigated whether an adjusted coil position still triggers reproducible diaphragmatic contractions after removal and repositioning in the same configuration. The knowledge gained will be used to further develop the technique and to prepare a study in critically ill, ventilated patients where the diaphragmatic muscle is to be treated preventively by stimulating the phrenic nerve, in order to prevent atrophy of the muscle.

NCT ID: NCT01096875 Completed - Clinical trials for Coronary Artery Bypass Surgery

Effects of Atorvastatin on Endothelial Progenitor Cells After Coronary Surgery

Start date: February 2010
Phase: Phase 4
Study type: Interventional

Experimental data have demonstrated favourable effects of statins on endothelial progenitor cell (EPC) mobilization from the bone marrow, and cardiac homing. The purpose of the present prospective randomized controlled trial is to determine the effects of aggressive atorvastatin treatment (40 mg daily 2-weeks prior to surgery) on the number of endothelial progenitor cells (EPCs) after cardiopulmonary bypass by comparing with placebo.

NCT ID: NCT00355173 Completed - Clinical trials for Elective Surgical Procedure

Pilot Study to Assess the Efficacy and Safety of the Lubo Cervical Collar

Start date: May 2006
Phase: Phase 1
Study type: Interventional

The Lubo cervical collar is a device that simultaneously maintains cervical spine control and keeps an open airway in a non-invasive manner. The purpose of the device is to manage cervical spine control and airway protection in the trauma patient.