The Effect of Local Injectet GH on the Collagen Synthesis in the Ligamentum Patella

Elderly Clinical Trial

Official title:

The Effect of Local Injectet GH on the Collagen Synthesis in the Ligamentum Patella

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01158612
• Other study ID #: H-2-2010-039
• Status: Completed
• Phase: N/A
• First received: July 7, 2010
• Last updated: November 4, 2011
• Start date: August 2010
• Est. completion date: August 2011

Study information

• Verified date: November 2011
• Source: University of Aarhus
• Contact: n/a
• Is FDA regulated: No
• Health authority: Denmark: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached. The purpose of this study is to examine the effect of local injection of human Growth Hormone on tendon collagen synthesis.

Description:

Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached. The purpose of this study is to examine the effect of local injection of human Growth Hormone on tendon collagen synthesis.

in order to investigate the collagen synthesis potential and the influence of growth hormone, 12 elderly males age > 50 year, is enrolled in this study.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: August 2011
• Est. primary completion date: July 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 55 Years to 70 Years

Eligibility

Inclusion Criteria:

• BMI 18.5 - 25.0

Exclusion Criteria:

• earlier knee injury

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Elderly
• Growth Hormone

Intervention

Drug:
• Growth Hormone
infusion of Growth hormone in the patella tendon.

Locations

Country	Name	City	State
Denmark	Århus universitetshospital nørrebrogade 44	Århus C

Sponsors (2)

Lead Sponsor	Collaborator
University of Aarhus	Bispebjerg Hospital

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	• Fraktionele collagen protein synthesis in human patella tendon		01122010	No