Effects of Unilateral WBV on Muscleactivity of Contralateral Hip Adductor

Effects of Vibration Clinical Trial

— WBV-BM  

Official title:

The Effects Of Femur On The Resting Myoelectrical Activity Of Contralateral Adductor Muscle During Unilateral Lower Extremity Vibration: Bone Myoregulation Reflex

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01419782
• Other study ID #: BEAH FTR-5
• Status: Completed
• Phase: N/A
• First received: August 17, 2011
• Last updated: May 6, 2013
• Start date: March 2011
• Est. completion date: December 2012

Study information

• Verified date: May 2013
• Source: Bagcilar Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Turkey: Ministry of Health
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to investigate effects of femur exposed to unilateral vibration on the rest muscle electrical activity of contralateral hip adductors and contralateral soleus H-reflex in young adult men.

This study hypothesize that femur exposed to unilateral vibration may affect the rest muscle electrical activity of contralateral hip adductors. Vibration can effectively enhance muscle strength and power. Previous studies have shown that vibration increases muscle electromyographic (EMG) activity. It has been showed that bone has an effect on the increase in muscle EMG activity caused by vibration in healthy young adults in a study. In this study, it was reported that vibrations-induced increases in muscle electrical activity of flexor carpi radialis (FCR) was related to ultradistal radius bone mineral content (BMC) and the FCR H-reflex was suppressed or depressed during vibration. This findings were reported to support the assumption that the bone exposed to cyclic mechanical loading may neuronally regulate muscle activity.

Description:

A total of 20 voluntaries are planned to include in this study.

Vibration will be applied the right lower extremity by whole-body vibration (PowerPlate Pro). Cases will stand on vibration plate. WBV will be applied at a frequency of 40 Hz and amplitude of 2 mm for 60 seconds. WBV will be applied one session only.

The rest muscle electrical activity of ipsilateral and contralateral hip adductor muscles at rest will be measured by PowerLab (data acquisition system, ADInstruments, Australia) device.The rest-EMGrms will be measured at before and during vibration. We also evaluate a change in contralateral soleus H reflex during vibration.

Effects of bone on the rest muscle electrical activity will be assessed by hip bone mineral density, bone mineral content and serum sclerostin level. The right hip bone mineral density (BMD) and BMC will be evaluated by bone densitometer (Norland). Plasma sclerostin level will be measured by using Human Sclerostin ELISA kıt before and after vibration.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: December 2012
• Est. primary completion date: November 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• Age: 20-40 yrs

• Gender: Male

• Volunteer

• Healthy status: Patients having hypoesthesia in his leg and Healthy subjects

• Dominant hand:Right-handed

Exclusion Criteria:

• Bone diseases (osteoporosis, osteomalacia, paget's disease, neoplasm, etc),

• Systemic diseases (cardiovascular, endocrine, infections etc),

• Myopathy-tendinopathy

• Lower limb joint disease

• Vertigo

• Obesity (BMI >30 kg/m2)

• Professional sportsman

• Male doing regular sports activities

• Skin disease in lower limb

• Non-cooperative subject

• Hemolysis of blood sample

Study Design

Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Bone Mass
• Effects of Vibration

Intervention

Other:
• Whole-body vibration
Frequency: 40 Hz, vibration amplitude: 2 mm, duration: 60 sec

Locations

Country	Name	City	State
Turkey	Bagcilar Training & Research Hospital	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Bagcilar Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Vibration-induced contralateral muscle electrical activity		3 month	No