Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions

Effects of the Elements Clinical Trial

Official title:

Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions in the Presence of Hydroxyapatite, Nanohydroxyapatite and Combination of Nanohydroxyapatite and Platelet-rich Fibrin. A Clinical Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05100615
• Other study ID #: 238
• Status: Recruiting
• Phase: N/A
• Start date: November 2021
• Est. completion date: May 2022

Study information

• Verified date: October 2021
• Source: Minia University
• Contact: Amira Elkholly, PHD
• Phone: +201001902507
• Email: dr.amiraelkholly[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

recruited patients with periapical lesions will be divided into three groups and surgically treated with three types of bone graft (hydroxyappatite, nanohydroxyappatite and PRF WITH NANOHYDROXTAPPATITE) and then evaluated for month, three months and six months for the healing of periapical bone

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 24
• Est. completion date: May 2022
• Est. primary completion date: May 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 45 Years

Eligibility

Inclusion Criteria:

• The patient will be in range of 20-45 years of age at the time of treatment, having periapical lesions starting from 5mm or more in diameter related to failed endodontically treated single canaled teeth.

Exclusion Criteria:

• Any systemic debilitating disease such as:

Diabetes mellitus, renal disease, Liver disease or liver failure, Rheumatoid arthritis, Neoplastic disease or its treatment, chronic corticosteroid therapy, chronic hepatitis B or C , History of hepatitis A, pregnant females.

Related Conditions & MeSH terms

• Effects of the Elements

Intervention

Procedure:
• surgery
applying the graft inside bony defect after surgery

Locations

Country	Name	City	State
Egypt	Amira mohammed fathy Elkholly	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Minia University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	healing of periapical lesion	change in size of bony defect	interappointment at 1 month, 3 months and 6 months