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Edema clinical trials

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NCT ID: NCT04215692 Recruiting - Fluid Overload Clinical Trials

Lung Ultrasound-guided Fluid Therapy in Pediatric Intensive Care Unit Patients

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

A randomized clinical trial to evaluate the effect of using pulmonary ultrasound to guide fluid therapy on distinct variables.

NCT ID: NCT04205253 Completed - Edema Clinical Trials

Tongue Depressor-related Ischemia-Reperfusion Injury in Tongue

Start date: October 1, 2018
Phase:
Study type: Observational

This study aimed to detect tongue edema associated with the pressure exerted by a rigid direct laryngoscope by measuring the tongue area using USG in patients undergoing suspension laryngoscopy (SL) procedures.

NCT ID: NCT04191629 Recruiting - Clinical trials for Fuchs' Endothelial Dystrophy

Phase 1 Study to Evaluate the Safety and Tolerability of EO1404 in the Treatment of Corneal Edema

Start date: May 4, 2016
Phase: Phase 1
Study type: Interventional

Single center, phase 1 study to evaluate the safety and tolerability of EO1404 in subjects with corneal edema secondary to pseudophakic bullous keratopathy or Fuch's endothelial dystrophy.

NCT ID: NCT04187443 Recruiting - Clinical trials for Diabetic Retinopathy

MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema

Start date: June 2, 2020
Phase: Phase 1
Study type: Interventional

This is an open label dose-escalation study to evaluate the safety and treatment benefits of MS-553 in treatment-naive diabetic retinopathy patients with central involved macular edema. Fifteen subjects with diabetic macular edema will be enrolled into each of three dose cohorts and will receive oral administration of MS-553 for 8 weeks.

NCT ID: NCT04186598 Completed - Clinical trials for Continuous Positive Airway Pressure

Evaluating the Utility of Continuous Positive Airway Pressure in the Treatment of High Altitude Pulmonary Edema

Start date: January 20, 2020
Phase: N/A
Study type: Interventional

The primary objective is to evaluate the efficacy of continuous positive pressure on resolution of high-altitude pulmonary edema vs high flow oxygen. The secondary objective is to derive an incidence of high-altitude pulmonary edema based on the elevation and timing from which the subject arrives. Additionally, in a convenience sample of the base study population, an ultrasound evaluation for the presence of B lines in the lungs will be conducted after 2 hours.

NCT ID: NCT04164927 Completed - Exercise Clinical Trials

The Effects of Manual Lymphatic Drainage and Kinesiotaping on Lower Extremity Edema

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

Significant trauma and muscular tightness often result during Total Knee Arthroplasty (TKA) surgery and thus act to restrict tissue fluid movement resulting with lower extremity edema. Kinesio Taping® is applied directly on the skin for restoration of normal fluid perfusion, removing congestion of lymphatic fluid or hemorrhages. In addition Manual Lymphatic Drainage (MLD) enhances blood circulation and stimulates the lymphatic movement and unblocks lymphatic territories. The aim of the study was to investigate the effectiveness of Kinesio Taping® and MLD in reducing postoperative edema and pain in the early stage after TKA.

NCT ID: NCT04151407 Recruiting - Clinical trials for Diabetic Macular Edema

The Study of Drug 601 in Patients With Diabetic Macular Edema (DME)

Start date: March 8, 2019
Phase: Phase 1
Study type: Interventional

Observe the safety and tolerability of the single and multiple doses of 601 in DME patients; study the pharmacokinetic characteristics of single and multiple doses of 601, Observe the Preliminary efficacy of 601 multiple injections with different doses in the treatment of patients with DME.

NCT ID: NCT04151160 Completed - Clinical trials for Congenital Heart Disease

Point of Care Ultrasound Measurements of Perioperative Edema in Infants With Congenital Heart Disease

Start date: January 13, 2020
Phase:
Study type: Observational

Babies can be born with heart problems and sometimes need a heart surgery to fix the heart problem. Heart surgery can cause swelling from the build-up of extra fluid. Swelling can make it harder for babies to breath and has to be treated with medicine called diuretics. Swelling is hard to measure in babies, so it can be hard to know how much diuretic they need to treat the swelling. The investigators are looking for a better way to measure swelling in babies who have had heart surgery. Ultrasound uses sound waves to take pictures of the inside of the body. Ultrasound is used to take pictures of babies before they are born and to take pictures of their heart after they are born. New ultrasound software has been made from a company called MuscleSound that can quickly measure the amount of swelling in adults, usually in less than 2 minutes. This software has not yet been used to measure swelling in kids. This study plans to learn more about swelling in babies and will try to measure swelling in babies before and after heart surgery with the new ultrasound software. The study will also make the same measurements in babies who do not have heart disease to compare to babies having heart surgery.

NCT ID: NCT04148950 Completed - Clinical trials for Varicose Veins of Lower Limb

Effects of Kinesio Taping Method on Functional Capacity and Quality of Life in Patients With Chronic Venous Disease

Start date: May 2013
Phase: N/A
Study type: Interventional

The purpose of this randomised and controlled study is to investigate the effects of Kinesio Taping method and compression stockings, combined with exercise therapy, on pain, edema, functional capacity and quality of life in patients with chronic venous disease. Therefore, the study compares effectiveness of these two methods for chronic venous disease.

NCT ID: NCT04140448 Recruiting - Macular Edema Clinical Trials

Ultra-wide-field Fluorescein Angiography in Patients With Macular Edema Secondary to Retinal Vein Occlusion

UWFA-RVO-ME
Start date: October 9, 2023
Phase:
Study type: Observational

This study mainly observed the ischemic index and vascular leakage index changes on ultra-wide field fluorescence angiography after anti-VEGF treatment , and whether these changes correlated with treatment efficacy in patients with macular edema secondary to retinal vein occlusion.