The Effectiveness of Eating Disorder Treatment

Eating Disorders Clinical Trial

Official title:

Effects of Family-based Treatment on Adolescent Outpatients Treated for Anorexia Nervosa in the Eating Disorder Unit of Helsinki University Hospital

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05734573
• Other study ID #: 653/13/01/03/2015/1
• Status: Completed
• Phase: N/A
• Start date: June 1, 2013
• Est. completion date: December 31, 2022

Study information

• Verified date: February 2023
• Source: Helsinki University Central Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Family-based treatment (FBT), a form of family therapy for eating disorders (ED) in young patients, has proven to be effective in numerous large-scale studies. This study aims to evaluate outcomes of the treatment for anorexia nervosa (AN) in a 'real-world' setting in a specialized outpatient clinic in Helsinki, Finland. Fifty-two young female patients seen for treatment between June 2013 and December 2017 were included in the study. Demographic and treatment characteristics, weight, and ED symptoms before and after treatment are reported

Description:

Aim: The naturalistic outcome of outpatient FBT for adolescent AN was investigated.

Methods: Fifty-two female patients and their families who received FBT at a tertiary eating disorders unit participated in the study. Data on their pre-treatment parameters, treatment details, and condition at the end of treatment (EOT) was collected from their medical records

Recruitment information / eligibility

• Status: Completed
• Enrollment: 52
• Est. completion date: December 31, 2022
• Est. primary completion date: December 31, 2017
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 13 Years to 18 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of Anorexia nervosa

• Admitted to FBT at the Eating Disorder Unit from June 1, 2013, through December 31, 2017

Exclusion Criteria:

• No exclusions

Related Conditions & MeSH terms

• Eating Disorders
• Feeding and Eating Disorders

Intervention

Behavioral:
• Family-based treatment
FBT is carried out by a family therapist who has received FBT training. The duration of FBT is commonly 6-12 months, in most cases comprising 10-20 sessions. At the beginning of treatment, there are weekly sessions; later in treatment, the sessions are less frequent. The patient and their family meet their psychiatrist every four to six weeks, and the family therapist also takes part in these meetings. The treatment is implemented in accordance with the FBT treatment manual.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Helsinki University Central Hospital

References & Publications (3)

Jones M, Volker U, Lock J, Taylor CB, Jacobi C. Family-based early intervention for anorexia nervosa. Eur Eat Disord Rev. 2012 May;20(3):e137-43. doi: 10.1002/erv.2167. Epub 2012 Mar 22. — View Citation

Lock J, Le Grange D. Family-based treatment: Where are we and where should we be going to improve recovery in child and adolescent eating disorders. Int J Eat Disord. 2019 Apr;52(4):481-487. doi: 10.1002/eat.22980. Epub 2018 Dec 6. — View Citation

Lock J. Family therapy for eating disorders in youth: current confusions, advances, and new directions. Curr Opin Psychiatry. 2018 Nov;31(6):431-435. doi: 10.1097/YCO.0000000000000451. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	% of patients with body weight normalization in treatment	Rate of patients with a normal body weight defined as a BMI over 18.5 at the end of treatment was calculated.	Treatment period, aprox. 1 year
Primary	% of patients with eating disorder symptoms at the end of treatment	The data of any eating disorder symptoms detected by a psychiatrist at the end of treatment were collected from the medical records, and the incidence was calculated.	Treatment period, aprox. 1 year
Primary	% of patients in need for a further treatment after the intervention	Rate of patients who still needed treatment after the FBT intervention from was assessed at the end of treatment. The data were obtained from the medical files of the patients.	Treatment period, aprox. 1 year