Eating Disorders Clinical Trial
Official title:
Epidemiological Studies of Eating Disorders in Gifted Dance Students: Prevalence Rate, Risk Factors and 1-Year Outcome (2nd Year).
This is the second-year part of a two-phase prospective epidemiological study as well as a
community case-controled study. The aims of the second year study are firstly, to
investigate the clinical course and 1-year outcome of eating disorders in the community, as
well as the prospective risk factors of eating disorders; secondly, a case-control design
involving with other psychiatric disorders from the same study population is used for risk
factors study.
The study subjects are gifted dance high school students who participated the first-year
study and are willing to participate the 2nd-year study (N=675). Screening questionnaires
for eating disorders and general psychiatric disorders are EAT, BITE and CHQ-12. Other
self-report questionnaires include perfectionism subscale of Eating Disorder Inventor-I
(EDI), Rosenberg Self-esteem Scale (RSE), Eyseck Personality Scale, Pubertal Develoment
Scale, and body figure test. Subjects who received interviews at the first-year study and
those whose scores are above the threshold of the screening questionnaires need to receive
interviews at 2nd phase. The criteria of interview threshold included EAT≧20+ BMI<18.5Kg/m2,
symptom scale of BITE ≧15 and/or severity scale of BITE≧5, and CHQ ≧4. The content of
interview included structured diagnostic interview (SCID-IP 1995) as well as risk factors
assessment. Each time a subject with bulimia nervosa was recruited, one matched control
subject with no mental illness general psychiatric diagnosis was sought from the same class
or school. Potential psychiatric control subjects were identified from their scores on the
CHQ. The psychiatric control subjects were required to have no current or past eating
disorders. The contents of risk factor assessments include personal vulnerability and family
problems.
The relationships between individual risk factors and case status were assessed by
univariate analysis. Conditional logistic analysis was used for multivariate analysis of
risk factors prediction for eating disorders. To assess the relative importance of different
types of exposure, the relationship between case status and exposure in each domain were
first assessed by univariate analysis and then in multivariate stepwise regression analyses.
This is the second-year part of a two-phase prospective epidemiological study as well as a
community case-controled study. The aims of the second year study are firstly, to
investigate the clinical course and 1-year outcome of eating disorders in the community, as
well as the prospective risk factors of eating disorders; secondly, a case-control design
involving with other psychiatric disorders from the same study population is used for risk
factors study.
The study subjects are Taiwanese gifted dance high school students.Parental informed consent
for nonpartipation was delivered 3 days before study started. Screening questionnaires for
eating disorders and general psychiatric disorders included EAT(Eating Attitude Test),
BITE(Bulimic Investigatory Test, Ediburgh BITE) and CHQ-12(Chinese Health Questionnaire).
Other self-report questionnaires include perfectionism subscale of Eating Disorder
Inventor-I (EDI), Rosenberg Self-esteem Scale (RSE), Eyseck Personality Inventory, Pubertal
Develoment Scale, and body figure test. Subjects who received interviews at the first-year
study and those whose scores are above the threshold of the screening questionnaires need to
receive interviews at 2nd phase. The criteria of interview threshold included EAT≧20+
BMI<18.5Kg/m2, symptom scale of BITE ≧15 and/or severity scale of BITE≧5, and CHQ ≧4. The
content of interview included structured diagnostic interview (SCID-IP 1995) as well as risk
factors assessment. Each time a subject with bulimia nervosa was recruited, one matched
control subject with no mental illness general psychiatric diagnosis was sought from the
same class or school. Potential psychiatric control subjects were identified from their
scores on the CHQ. The psychiatric control subjects were required to have no current or past
eating disorders. The contents of risk factor assessments include personal vulnerability and
family problems.
The relationships between individual risk factors and case status were assessed by
univariate analysis. Conditional logistic analysis was used for multivariate analysis of
risk factors prediction for eating disorders. To assess the relative importance of different
types of exposure, the relationship between case status and exposure in each domain were
first assessed by univariate analysis and then in multivariate stepwise regression analyses.
;
Observational Model: Defined Population, Time Perspective: Cross-Sectional
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