Screening for Early Gastric Cancer in Shaanxi Province

Early Gastric Cancer Clinical Trial

Official title:

Screening for Early Gastric Cancer in Shaanxi Province

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05291728
• Other study ID #: 2021036
• Status: Recruiting
• Start date: October 1, 2020
• Est. completion date: October 1, 2026

Study information

• Verified date: February 2022
• Source: Second Affiliated Hospital of Xi'an Jiaotong University
• Contact: jinhai Wang, MD
• Phone: 029-87679335
• Email: jinhaiwang[@]hotmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study collect the relevant data of local residents over 20 years old in 11 regions of Shaanxi Province, The basic information of the subjects was collected by filling in the questionnaire, and serum helicobacter pylori antibody detection was completed at the same time. The expert group determined the high-risk population of gastric cancer after comprehensive evaluation. All the high-risk population of gastric cancer without contraindications underwent electronic gastroscopy in the designated hospital after signing the informed consent. By collecting and analyzing data, early gastric cancer screening was completed and a new gastric cancer risk assessment model was established to evaluate the prevalence of dyspepsia, gastroesophageal reflux disease and precancerous lesions in the natural population of Shaanxi Province, as well as helicobacter pylori infection, radical treatment and recurrence rate.

Description:

From October 2020 to October 2026, after obtaining the informed consent of local residents over 20 years old in 11 regions of Shaanxi Province, the subjects' social demographic characteristics, living and eating habits, and previous diseases were collected by filling in questionnaires, and serum helicobacter pylori antibody was detected at the same time. After comprehensive assessment by the expert group, the high-risk population of gastric cancer was determined. All high-risk population of gastric cancer without contraindications underwent electronic gastroscopy in designated hospitals after signing informed consent. By collecting and analyzing data, early gastric cancer screening was completed and a new gastric cancer risk assessment model was established to evaluate the prevalence of dyspepsia, gastroesophageal reflux disease and precancerous lesions in the natural population of Shaanxi Province, as well as helicobacter pylori infection, radical treatment and recurrence rate. In this project, the research group was responsible for formulating the plan, designing the questionnaire, and conducting quality control and grass-roots guidance tour. Guanghua Science and Technology Foundation provided public welfare assistance, and distributed and collected questionnaires with the assistance of grass-roots clinics. Finally, the research group sorted out and analyzed the data.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 12500000
• Est. completion date: October 1, 2026
• Est. primary completion date: October 1, 2026
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Local resident over 20 years old.

• Obtain verbal informed consent of the subject.

Exclusion Criteria:

• Refused to participate in this research project.

• Questionnaires or serological tests for helicobacter pylori antibodies were not completed.

• This study was not completed due to other reasons.

Related Conditions & MeSH terms

• Early Gastric Cancer
• Stomach Neoplasms

Locations

Country	Name	City	State
China	The second affiliated hospital of xi'an jiaotong university	Xi'an	Shaanxi

Sponsors (1)

Lead Sponsor	Collaborator
Second Affiliated Hospital of Xi'an Jiaotong University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the detection rate of early gastric cancer	Patients at high risk of gastric cancer were assessed by questionnaire and Hp test results, and then underwent gastroscopy.Then analyse the detection rate of early gastric cancer.	2020.10.01-2026.10.01
Secondary	the prevalence of dyspepsia, gastroesophageal reflux disease and precancerous lesions in the natural population of Shaanxi Province, as well as the prevalence of helicobacter pylori infection, radical treatment and recurrence rate.	Basic information, Hp antibody detection results and gastroscopy results were collected,and then analyse the prevalence of dyspepsia, gastroesophageal reflux disease and precancerous lesions in the natural population of Shaanxi Province, as well as the prevalence of helicobacter pylori infection, radical treatment and recurrence rate.	2020.10.01-2026.10.01