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E-cigarette Use clinical trials

View clinical trials related to E-cigarette Use.

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NCT ID: NCT06196489 Recruiting - E Cigarette Use Clinical Trials

Adapting an Intervention for Vaping in Young Veterans

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The objective of this proposal is to adapt an evidence-based combustible tobacco counseling intervention following an evidence-based process to include e-cigarette use and update its components for emerging adults (EA). 1. Examine factors related to e-cigarette use, barriers to cessation, and facilitators of use of cessation services among an EA population. 2. Beta-test an initial version of the intervention, delivered via video telehealth and telephone, to examine usability and acceptability.

NCT ID: NCT06159608 Recruiting - E-cigarette Use Clinical Trials

Sex Differences in the Vascular Effects of E-cigarette Use

Start date: November 2024
Phase: Early Phase 1
Study type: Interventional

The use of electronic nicotine delivery systems, or e-cigarettes - colloquially referred to as "vaping" - in the United States has increased exponentially since their introduction to the US market in 2007. Prevalence of ever and current e-cigarette use is highest among teenagers and young adults with 16-28% of this population having reported vaping. While the majority of e-cigarette users are current tobacco smokers, 32.5% of current e-cigarette users are never- or former-smokers, representing a growing population of young adults who exclusively vape. While e-cigarettes have been marketed as a safer alternative to tobacco cigarettes, clinical studies examining these claims are limited. Cardiovascular disease (CVD) is the primary cause of premature death among tobacco cigarette smokers and reductions in vascular endothelial function, a significant predictor of future CVD, are detectible in otherwise healthy young adults who smoke. Despite the explosion in e-cigarette use among young adults, the health effects - especially the effects on mechanisms of vascular function - of these devices remain relatively unexplored. In this study, we use the blood vessels in the skin as a representative vascular bed for examining mechanisms of microvascular dysfunction in humans. Using a minimally invasive technique (intradermal microdialysis for the local delivery of pharmaceutical agents) we examine the blood vessels in a dime-sized area of the skin in otherwise healthy young (18-24yrs) chronic e-cigarette users. Local heating of the skin at the microdialysis sites is used to explore differences in mechanisms governing microvascular control. As a compliment to these measurements, we also draw blood from the subjects to measure circulating factors that may contribute to cardiovascular health and examine markers of inflammatory activation. We will also collect urine from female participants to measure estradiol.

NCT ID: NCT06066996 Recruiting - E-cigarette Use Clinical Trials

Evaluation of the Electronic Cigarette Withdrawal Syndrome

Start date: November 28, 2023
Phase: Early Phase 1
Study type: Interventional

The goal of this project is to rigorously evaluate the nature of e-cigarette withdrawal in exclusive e-cigarette users during a monitored abstinence period and the role of nicotine in the expression of this withdrawal syndrome.

NCT ID: NCT06027840 Recruiting - Smoking Cessation Clinical Trials

Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use

Start date: April 1, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to understand whether concurrent treatment for cigarettes and e-cigarettes in which an individual quits both products at the same time (QUIT-C) or sequential treatment in which an individual quits cigarettes first followed by e-cigarettes is more effective for quitting both products. The study will also compare the effect of treatment on health-related biomarkers. All participants will receive varenicline, a medication used to treat tobacco use dependence, counseling, and cessation resources (i.e., links to text-based support, self-change booklet). Varenicline helps to reduce cravings for tobacco use and decreases the pleasurable effects of cigarettes and other tobacco products.

NCT ID: NCT05906082 Recruiting - E-cigarette Use Clinical Trials

Vape-Free Text-Messaging: Pilot Study

Start date: May 25, 2023
Phase: N/A
Study type: Interventional

This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messaging intervention with young adults in rural areas.

NCT ID: NCT05864586 Recruiting - E-cigarette Use Clinical Trials

Developing E-liquid Product Standards (Sweet Spot Study)

Start date: May 30, 2023
Phase: N/A
Study type: Interventional

The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of smoking and older adult smokers.

NCT ID: NCT05586308 Recruiting - Clinical trials for Implementation Science

Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation

Start date: October 7, 2023
Phase: N/A
Study type: Interventional

This study aims to evaluate the feasibility and compare the preliminary effect of vaping cessation program consisting of media literacy education and real-time text messaging support and leverage insights from behavioral economics to enhance social and financial incentives to improve program engagement, and eventually abstinence. Our hypotheses are that 1) the Combined arm is associated with improved vaping abstinence to the Media literacy and Financial incentive arms; and 2) the financial incentive-related arms (either Combined or Financial incentive) enhance engagement compared to the non-incentive related arms.

NCT ID: NCT05458895 Recruiting - E-cigarette Use Clinical Trials

Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth

Start date: December 2, 2021
Phase: N/A
Study type: Interventional

This clinical trial examines the influence of nicotine form, concentration, and e-liquid flavor on youth vaping behavior, as well as the heart and lung effects associated with this behavior. Electronic cigarette (e-cig) "vaping", while being promoted as a safer alternative to conventional cigarettes, has disproportionately attracted adolescents and young adults ("youth"). This trial may help researchers understand how nicotine form, concentration, and flavor affects people's vaping behaviors and health.

NCT ID: NCT05112562 Recruiting - Clinical trials for Tobacco Use Cessation

Attentional Bias Modification Training for E-cigarette Users

Start date: June 9, 2021
Phase: N/A
Study type: Interventional

Aims are to (1) evaluate attentional bias to e-cigarette cues between the intervention and control groups at post-intervention as compared to the pre-intervention; and (2) test the feasibility and efficacy of the intervention at post-intervention. To accomplish these aims, a theory-driven parallel, controlled 2-arm randomized clinical trial will be conducted with young adult e-cigarette users (approximately N = 50). Outcomes are attentional bias to e-cigarette cues and abstinence outcomes including nicotine dependence, and arousal/urges for e-cigarette use.

NCT ID: NCT04616313 Recruiting - E Cigarette Use Clinical Trials

Novel Pulmonary Imaging of Lung Structure and Function in E-cigarette Smokers

Start date: January 17, 2023
Phase:
Study type: Observational

This is a longitudinal study of the long-term health impact of e-cigarette smoking on the lungs. Participants will be followed over a period of 5 years, and impacts of e-cigarette smoking on the lungs will be measured with magnetic resonance imaging (MRI) using hyperpolarized xenon-129 gas, pulmonary function tests, exercise capacity, computed tomography images and questionnaires.