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Dysphonia clinical trials

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NCT ID: NCT02061943 Withdrawn - Spasmodic Dysphonia Clinical Trials

Examining the Spasmodic Dysphonia Diagnosis and Assessment Procedure (SD-DAP) for Measuring Symptom Change

Start date: October 2015
Phase: N/A
Study type: Observational

This is a study of patients with spasmodic dysphonia to determine how best to measure the severity of the disorder in patients. It addresses which characteristics of speech are the best indicator of whether or not a particular treatment has benefited a person with spasmodic dysphonia. We hope to recruit 20 participants each at 2 different centers. The evaluation for each participant will be done on a two visits, one just before and another several weeks after treatment.

NCT ID: NCT01999855 Terminated - Clinical trials for Asthmatic Patients and Control Group

Frequency of Dysphonia in Asthmatic Patients

Start date: December 2013
Phase: N/A
Study type: Interventional

For many years, it is known that asthmatics have more often dysphonia. However, no study has so far analyzed the reality of dysphonia in asthmatic by making phoniatric tests. The etiology of dysphonia in asthmatic remains controversial. Indeed, for a long time, inhaled corticosteroids have been considered as responsible for organic abnormalities of the vocal cords. We hypothesized that women with asthma have more often dysphonia, and that dysphonia is rather functional origin.

NCT ID: NCT01990781 Completed - Clinical trials for Postoperative Sore Throat, Cough, Hoarseness

Effect of Intravenous Lidocaine and Dexamethasone Combination on Postoperative Sore Throat, Cough and Hoarseness.

Start date: December 2013
Phase: Phase 4
Study type: Interventional

Post operative sore throat (POST) following tracheal intubation is a common problem causing dissatisfaction and discomfort to the patients. Prophylactic use of both lidocaine and dexamethasone has been used independently for this purpose. However, there is no study assessing the synergistic analgesic effects of lidocaine and dexamethasone for POST. The purpose of this study is to compare the effect of lidocaine, dexamethasone and lidocaine dexamethasone combination on the incidence and severity of POST.

NCT ID: NCT01988207 Not yet recruiting - Clinical trials for Muscle Tension Dysphonia

Treating Laryngeal Hyperfunction With Flow Phonation

Start date: December 2013
Phase: N/A
Study type: Interventional

The purposes of the proposed study are: a) to determine whether Flow Phonation can decrease Laryngeal Resistance (Rlaw) in patients with Muscle Tension Dysphonia (MTD); and b)establish the relationship between changes in measures of Rlaw and phonatory airflow to endoscopic, perceptual, acoustic, and handicap assessment ratings. MTD can have a debilitating effect on individuals who rely on their voices the most—teachers, preachers,salespeople, singers—costing them time, money, and even their jobs. It can lead to vocal fatigue, pain, and complete loss of voice. While treatments have emerged with some promising effects, no treatments have proven to have long-term benefits to all patients. Our preliminary data demonstrate Flow Phonation training resulted in significant decreases in Laryngeal Resistance to phonatory airflow with associated improvements in voice quality and voice handicap ratings. Sample size for our pilot study was small; no control group was utilized; and outcome measures were limited. In the proposed investigation, a larger sample will be obtained, a control group of participants receiving only Vocal Hygiene Training will be used for comparison during the first 3 weeks, and a wider range of outcome measures will be included over a longer period of time (1 year).

NCT ID: NCT01961297 Completed - Spasmodic Dysphonia Clinical Trials

Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response

Start date: July 2012
Phase: Phase 2
Study type: Interventional

The proposed research aims to determine brain abnormalities in patients with spasmodic dysphonia (SD) and voice tremor (VT) as the basis for characterization of central mechanisms underlying symptom improvement following the use of sodium oxybate, a novel oral medication for the treatment of ethanol-responsive dystonia. The proposed research is relevant to public health because the elucidation of disorder-specific mechanistic aspects of brain organization in SD vs. SD/VT is ultimately expected to lead to establishment of enhanced criteria for clinical management of these disorders, including differential diagnosis and treatment. Thus, the proposed research is relevant to the part of NIH's mission that pertains to developing fundamental knowledge that will help to reduce the burdens of human disability.

NCT ID: NCT01626365 Completed - Sore Throat Clinical Trials

Thermosoftening of Double-lumen Tube to Reduce Sore Throat

Start date: May 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of double-lumen tube thermosoftening before intubation to reduce postoperative hoarseness and sore throat.

NCT ID: NCT01419444 Completed - Clinical trials for Muscle Tension Dysphonia

Telemedicine Versus Traditional Treatment of Muscle Tension Dysphonia

Start date: August 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this research is to determine whether treatment of voice disorders can be provided just as effectively using telemedicine as it can using on-site, traditional therapy. An exercise protocol for improving airflow with voicing has been demonstrated to be effective in a prior UAMS investigation (Protocol 107454). These exercises are used as part of the normal clinic routine at UAMS working with individuals with voice problems. The three exercises used are: gargling with and without voicing; cup bubble blowing with and without voicing; and, stretch and flow exercises, which involves the use of a piece of tissue to provide visual biofeedback on the ability to use proper airflow with voicing. The purpose of the exercises is to increase airflow and breathiness in the voice and reduce muscle tension. In addition, patients will be taught to use a "confidential voice" or gentle voice during speaking. The investigators voice patients come from all over the state and many cannot return for regular treatment. Developing a way to provide treatment to them closer to home could greatly improve quality of care and quality of life. Twenty participants will participate for 12 sessions each. All participants will be evaluated at UAMS before and after treatment as part of standard care and will, upon consent, be randomized to receive treatment via telemedicine at an AHEC site or at UAMS Medical Center. Homework will be provided along with log sheets. Results of airflow measures using an airflow-recording device (Viasys, KAY/PENTAX) pre- and post treatment will determine whether telemedicine results are equal to results of traditional, on-site treatment. The investigators hypothesize that results from treatment using telemedicine will be equivalent to results for onsite, traditional treatment.

NCT ID: NCT01385969 Completed - Dysphagia Clinical Trials

LMA Cuff Pressure and LMA-induced Complications

Start date: June 2011
Phase: N/A
Study type: Observational

The purpose of this study is to determine if using 20 mL B.Braun syringes to inflate LMAs and allowing them to recoil will put the pressure of the LMA cuff within the safety range. It will also determine if remaining within this safety range has an effect on complications after surgery..

NCT ID: NCT01305265 Completed - Dysphagia Clinical Trials

Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique

Start date: November 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to test whether the incidence of sore throat and other tracheal co-morbidities such as dysphagia and hoarseness can be lessened by use of a cuff manometer at the beginning of surgery to inflate to the proper pressure compared to the standard technique. The investigators hypothesis is that inflation of the endotracheal balloon using a cuff manometer immediately after intubation will reduce the incidence of sore throat and other tracheal co-morbidities.

NCT ID: NCT01017055 Recruiting - Dysphagia Clinical Trials

Voice and Swallowing Outcomes Following Revision Anterior Cervical Spine Surgery

Start date: October 26, 2009
Phase:
Study type: Observational

Evaluate voice and swallowing outcomes post operatively.