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A Study to Evaluate the Effects of ABX-1431 on Patients With Functional Dyspepsia

Dyspepsia Clinical Trial

Official title:
A Single-Dose Study to Evaluate the Effects of ABX-1431 on Gastric Accommodation and Nutrient Volume Tolerance in Patients With Functional Dyspepsia

Clinical Trial Summary

A Single-Dose Study to Evaluate the Effects of ABX-1431 on Gastric Accommodation and Nutrient Volume Tolerance in Patients with Functional Dyspepsia.

Clinical Trial Description

This is a single dose, randomized, placebo-controlled, two period crossover study. This study will assess the effects of ABX-1431 on gastric physiology in patients with functional dyspepsia, who have clinical evidence of impaired gastric accommodation with meals.

All patients will undergo a screening visit for enrollment criteria. Eligible patients will be treated with a single dose of ABX-1431 HCl or placebo followed by IGP measurement, measured with a high resolution manometry probe during a nutrient volume tolerance test. After a washout period of at least one week, patients will undergo identical procedures with the other treatment.

This study will enroll 12 functional dyspepsia (FD) patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02875678
Study type Interventional
Source Abide Therapeutics
Contact
Status Terminated
Phase Phase 1
Start date November 22, 2016
Completion date August 7, 2017
View Details
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