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Dyspepsia clinical trials

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NCT ID: NCT00148603 Completed - Dyspepsia Clinical Trials

Montelukast in the Treatment of Duodenal Eosinophilia

Start date: September 2005
Phase: N/A
Study type: Interventional

This is a single site study of the effect of montelukast on eosinophil and mast cell counts and activation in the lining of the duodenum in 24 children with dyspepsia in association with duodenal eosinophilia in association with measuring the concentration of the medication in the lining of the duodenum. Patients will be endoscoped with biopsies obtained from the duodenum as part of routine clinical care. Participants in the study will then receive montelukast daily and the endoscopy with biopsies will be repeated on day 21 to measure cell counts and activation and tissue montelukast levels. Cell counts and measures of activation will be compared to pre-treatment levels.

NCT ID: NCT00132171 Completed - Clinical trials for Helicobacter Pylori Infection

Helicobacter Pylori Eradication With a New Sequential Treatment

Start date: January 2001
Phase: Phase 3
Study type: Interventional

Eradication rates of Helicobacter pylori (H. pylori) with standard triple therapy are disappointing, and studies from several countries confirm this poor performance. The study aimed to assess the eradication rate of a new sequential treatment regimen compared with conventional triple therapy for the eradication of H. pylori infection.

NCT ID: NCT00120315 Completed - Dyspepsia Clinical Trials

Proton Pump Inhibitor Treatment Stop

Start date: December 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine how many chronic users of antisecretory medication can stop after a test for a bacteria associated with peptic ulcer disease. This is evaluated in a discontinuation trial.

NCT ID: NCT00115362 Completed - Dyspepsia Clinical Trials

Serotonin Effect in Functional Dyspepsia

Start date: July 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether Efexor (venlafaxine) is effective in the treatment of functional dyspepsia.

NCT ID: NCT00112333 Completed - Dyspepsia Clinical Trials

Defining Central Circuits of Pain

Start date: October 2003
Phase: N/A
Study type: Interventional

The purpose of the study is to use functional Magnetic Resonance Imaging (MRI) to help us understand what parts of the subject's brain are involved when he experiences visceral pain, or pain in the gut. To stimulate the brain, he will be infused with a liquid meal (Ensure) into his stomach until he is maximally full. Magnetic resonance imaging (MRI) is a technique for making images (pictures) of the brain; it uses magnetic fields and radio waves and is not harmful. This study uses a new investigational technique called functional MRI (fMRI), which is a very fast MRI technique that will allow the investigators to evaluate changes in how blood flows to parts of his brain.

NCT ID: NCT00112203 Completed - Dyspepsia Clinical Trials

Long-Term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia

Start date: November 2004
Phase: Phase 3
Study type: Interventional

Itopride is a compound already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms of functional dyspepsia. Patients suffering from this condition have difficulties digesting food. Patients feel full after eating; they have bloating and have stomach pain. The goal of this study is to see if itopride helps to relieve the symptoms of functional dyspepsia on a long-term basis.

NCT ID: NCT00112190 Completed - Dyspepsia Clinical Trials

Effect of Itopride, on Symptoms of Functional Dyspepsia, Such as Indigestion, Bloating, Inability to Finish a Meal

Start date: July 2004
Phase: Phase 3
Study type: Interventional

Itopride is a new compound that is already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms of functional dyspepsia. Patients suffering from this condition have difficulties digesting food. They feel full after eating a few bites; they feel bloated and their stomachs hurt. The goal of this study is to see if itopride helps to relieve the symptoms of functional dyspepsia.

NCT ID: NCT00112177 Completed - Dyspepsia Clinical Trials

Effect of Itopride, on Symptoms of Functional Dyspepsia, Such as Indigestion, Bloating, Inability to Finish a Meal

Start date: July 2004
Phase: Phase 3
Study type: Interventional

Itopride is a new compound that is already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms of functional dyspepsia. Patients suffering from this condition have difficulties digesting food. They feel full after eating a few bites; they feel bloated and their stomachs hurt. The goal of this study is to see if itopride helps to relieve the symptoms of functional dyspepsia.

NCT ID: NCT00110968 Completed - Dyspepsia Clinical Trials

Long-term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia

Start date: September 2004
Phase: Phase 3
Study type: Interventional

Itopride is a compound already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms of functional dyspepsia. Patients suffering from this condition have difficulties digesting food. Patients feel full after eating, they have bloating and have stomach pain. The goal of this study is to see if Itopride helps to relieve the symptoms of functional dyspepsia on a long-term basis.

NCT ID: NCT00102310 Completed - Nausea Clinical Trials

YM443 in Subjects With Functional Dyspepsia

Start date: March 10, 2004
Phase: Phase 2
Study type: Interventional

The primary objective of this study will be to characterize the dose response profile of YM443 in subjects with functional dyspepsia (FD) to enable the selection of doses for the Phase 3 clinical trial.