Effect of Aerobic Training and Moringa Oleifera on Dyslipidemia and Cardiac Endurance

Dyslipidemias Clinical Trial

Official title:

Effect of Aerobic Training and Moringa Oleifera on Dyslipidemia and Cardiac Endurance

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04164771
• Other study ID #: NA 125
• Status: Not yet recruiting
• Phase: N/A
• Start date: February 2020
• Est. completion date: July 2020

Study information

• Verified date: December 2019
• Source: Aga Khan University
• Contact: Naseer Ahmed, Ph.D
• Phone: 03333382013
• Email: dr.naseer99[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Aerobic training is essential for maintaining and improving physical performance and has a positive effect on physiological functions as well as anthropometric characteristics. It also has positive effect on cardiovascular health and carries a number of beneficial effects on the whole body functions and systems. Aerobic training can also decrease the risk of heart disease in the individual's life.The Moringa leaves are the rich source of minerals, vitamins and other essential phytochemicals. Moringa leave have found to be very effective in many disease particularly diabetic, blood pressure, dyslipidemia and cancer.

Description:

Aerobic training is an important component for health in daily life as well as sports performance. Aerobic training improves overall health, reduces body fat, maintain body weight, resting blood pressure (systolic and diastolic), maximal oxygen consumption adequate blood supply and provision of oxygen to the body muscles .The studies reveal that aerobic training is valuable for improving cardiovascular health, fitness and quality of life. On account of lack of aerobic engagement around 17 % of the population suffer from heart related ailment, 12 % from diabetes and 10 % from breast cancer. American College of Sports Medicine suggested that 30 minutes of aerobic workout has progressive effects on physical fitness and especially on chronic diseases. Physically fit individuals have got the potential to affectively cope with stress and anxiety and coronary arteries diseases. Aerobic training can raise maximal oxygen uptake, which means body adapts to use oxygen more efficiently during physical activities. Resultantly, the heart becomes efficient and stronger; meaning that the heart doesn't have to work hard to pump blood in resting position. Aerobic training decreases resting heart rate and may increase blood volume and blood plasma. Moringa Oleifera a plant from the family Moringacea, its products are used as a health supplement introduced in Africa and south Asian countries to cure many diseases and improve health status . Moringa leaves are rich source of vitamins and protein. The Moringa oleifera leaves, flowers, seeds and pods are commonly used as vegetables diet in different regions of south Asia. Moringa plant products are sources of vitamin A, b, C and proteins, including the essential amino acids. Moringa Oleifera leaves can be merged in the feed of birds, animals and human which provide wonderful source of protein other than expensive ingredients. The Moringa oil is used in cooking products as well as for lubrication. There are scientific indications that Moringa Oleifera holds therapeutic potential for hyperlipidemia, diabetes and cardiovascular diseases. The use of herbal supplements has increased rapidly during the first decade of the twentieth century. The nutrients of Moringa are considered to be useful for disorders including skin disease, malnutrition and sexual problem.Different experimental studies has described that Moringa oleifera leaves have therapeutic potential for chronic hyperglycemia and dyslipidemia . Moringa Oleifera is used as a hypolipidemic medication to improve the lipid profile of rats fed on atherogenic diet. Moringa Oleifera intake is more effective in prevention than in treatment of hyperlipidemia.It is documented that overuse of Moringa supplements can cause high increase of iron. Hence, a daily 70 g quantity of Moringa is recommended to be batter and preventive for accumulation of nutrients.This research study is due to be conducted to determine the effect of aerobic training and Moringa Oleifera on dyslipidemia and cardiac endurance

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 120
• Est. completion date: July 2020
• Est. primary completion date: April 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 20 Years to 50 Years

Eligibility

Inclusion Criteria:

• Healthy and no medical conditions.

• LDL level should be 160-189 mg/dl

• HDL level should be < 40 mg/dl

• Tri glyceride level should be 200-499 mg/dl

• Total cholesterol level should be > 200 mg/dl).

• Beep Test score should be less than 10.5 or less than 40% vo2 max

Exclusion Criteria:

• Any disease condition as anemia, physical injuries, chronic disease

• Not capable of doing aerobic training

Related Conditions & MeSH terms

• Dyslipidemias

Intervention

Other:
• Aerobic training and Moringa Oleifera
Aerobic exercises/training refers to any type of rhythmic, continuous physical activities that use large group of muscles like walking, running, cycling, and swimming consuming additional amount of energy while Moringa Oleifera a plant from the family Moringacea, its products are used as a health supplement introduced in Africa and south Asian countries to cure many diseases and improve health status

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Aga Khan University	Muhammad Safdar Ali

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Positive effect of aerobic training and Moringa Oleifera on dyslipidemia and cardiac endurance	Change in level of HDL, LDL and triglyceride, impact on cardiac endurance	6 weeks