A Phase IIa Study of TAS-205 for Duchenne Muscular Dystrophy

Status Completed

Clinical Trial Summary

The objective of this study is to evaluate the efficacy after 24-week repeated oral doses of TAS-205 in patients with Duchenne Muscular Dystrophy (DMD) in an exploratory manner.

Clinical Trial Description

Duchenne Muscular Dystrophy (DMD) is the most common fatal genetic disorder diagnosed in childhood, affecting approximately 1 in 3,500 lives male births. DMD patients suffer from a relentless decline in muscle strength that impairs the ability of walking and breathing, resulting in their lives with wheelchairs and then loss of upper body function. The main objective of this study is to evaluate the efficacy after 24-week repeated oral doses of TAS-205 in patients with DMD in an exploratory manner. The objective of this study is also to evaluate the safety, the dose-response and the urinary excretion of pharmacodynamic (PD) marker after 24-week repeated oral doses of TAS-205 in DMD patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02752048
Study type	Interventional
Source	Taiho Pharmaceutical Co., Ltd.
Contact
Status	Completed
Phase	Phase 2
Start date	May 2016
Completion date	October 17, 2017

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