Dry Socket Clinical Trial
Official title:
Exploring the Efficacy of Pure Honey Dressing in Contrast to Alvogyl in the Resolution of Dry Socket: A Comparative Analysis
Dry socket, or Alveolar Osteitis, is the most common complication that can follow a tooth extraction. Over the years, various approaches have been employed to expedite the healing process and alleviate the associated symptoms. Among these, Alvogyl has been the most commonly used dry socket dressing all over the globe. However due to Alvogyl's potential side effect of causing a foreign body reaction & ultimately necrosis of the alveolar bone if left in the socket along with its high cost, scientists have sought to develop new techniques. Among them, Honey dressing has heralded promising properties in facilitating the resolution of dry socket, thus opening the window of a side-effect free natural viable alternative to Alvogyl. In this research, we aim to compare the efficacy of pure Honey as a dry socket dressing in comparison to Alvogyl.
Status | Not yet recruiting |
Enrollment | 40 |
Est. completion date | January 2025 |
Est. primary completion date | December 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility | Inclusion Criteria: 1. Patients over 18 years of age of both genders. 2. Patients who underwent extraction of teeth and were clinically diagnosed with dry socket at the OMFS department of NID, Multan. 3. Patients which give informed consent. Exclusion Criteria: 1. Patients below the age of 18 and above the age of 70. 2. Patients with various bone diseases, including osteoporosis & a history of taking oral or intravenous bisphosphonates 3. Patients with a history of radiotherapy on the head, neck, and jawbones were excluded from this study, 4. Patients with systemic diseases such as diabetes mellitus, hepatic dysfunctions, blood dyscrasias, and bleeding disorders 5. Patients with allergy to Ibuprofen & honey 6. Patients having symptoms similar to dry socket due to retained root pieces, oroantral communication, or any bony or soft tissue pathology by the help of a radiograph 7. Patients who did not give informed consent. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Watim Medical & Dental College |
Abu-Mostafa N, Al-Daghamin S, Al-Anazi A, Al-Jumaah N, Alnesafi A. The influence of intra-alveolar application of honey versus Chlorhexidine rinse on the incidence of Alveolar Osteitis following molar teeth extraction. A randomized clinical parallel trial — View Citation
Keshini MP, Shetty SK, Sundar S, Chandan SN, Manjula S. Assessment of Healing Using Alvogyl and Platelet Rich Fibrin in Patients with Dry Socket - An Evaluative Study. Ann Maxillofac Surg. 2020 Jul-Dec;10(2):320-324. doi: 10.4103/ams.ams_259_19. Epub 2020 — View Citation
Soni N, Singh V, Mohammad S, Singh RK, Pal US, Singh R, Aggrwal J, Pal M. Effects of honey in the management of alveolar osteitis: A study. Natl J Maxillofac Surg. 2016 Jul-Dec;7(2):136-147. doi: 10.4103/0975-5950.201354. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Pain relief | The patients will be requested to note daily pain records on a (0-10) visual analog scale, with 0 representing no pain and 10 representing the worst pain.. | Patients will be reviewed at 5 min post-medication, 30 min post-medication, 60 min post-medication, 2nd day post-medication, 4th day post-medication and 7th day post-medication. |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT03741894 -
Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery
|
Phase 4 | |
Recruiting |
NCT02678104 -
The Influence of Intra-alveolar Application of Honey on Healing Following Extraction
|
Phase 2 | |
Recruiting |
NCT05615272 -
Treatment of Alveolar Osteitis: Traditional or Regenerative?
|
N/A | |
Completed |
NCT03992144 -
Prevention of Dry Socket by Means of Single Preoperative Antibiotics Compared to Conventional Therapy
|
Phase 2 | |
Recruiting |
NCT05875506 -
Efficacy of Ozone Gel, Doxycycline Saturated Chitosan Dressing Versus Alveogyl in Pain Alleviation and Healing of Alveolar Osteitis
|
N/A | |
Completed |
NCT00118820 -
Antibiotic Efficacy in Third Molar Surgery
|
Phase 3 | |
Not yet recruiting |
NCT06452134 -
Evaluation the Effect of Coenzyme Q10 on Tissue Healing Process in Patients Undergoing Wisdom Tooth Extraction
|
Phase 4 | |
Completed |
NCT05984173 -
Role of Vitamin E in Reducing Dry Socket
|
Phase 4 | |
Completed |
NCT01292343 -
Triclosan Toothpaste and Third Molar Surgery
|
N/A | |
Recruiting |
NCT05536115 -
Impact of Treatment With ALVEOGYL in Patients With Post-extraction Dry Socket
|