Dry Eye Clinical Trial
Official title:
Dry Eye Evaluation System Based on Bioinformatics
Dry eye is a common ocular surface disease of multifactorial etiology characterized by
elevated tear osmolality and inflammation leading to a disrupted ocular surface. The latter
is a risk factor for ocular surface infection, yet overt infection is not commonly seen
clinically in the typical dry eye patient. This suggests that important innate mechanisms
operate to protect the dry eye from invading pathogens. Understand the pathogenesis of dry
eye will be the measure to prevention and treatment of dry eye.
In this essay, the investigators use the data of experiment in the patients with dry eye and
normal, acquire their tear production, tear film stability, and surface damage. The
investigators use weka to calculate the prediction accuracy of the 6 algorithm and select the
best one, optimize the parameters to get the final prediction accuracy.
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