Dry Eye Clinical Trial
Official title:
Tear Osmolarity Clinical Utility in Dry Eye Disease
Millions of people suffer from dry eye disease, causing symptoms such as redness, burning,
feeling of sand or grit in the eye and light sensitivity. Dry eye disease occurs when your
eyes do not produce enough tears or produce poor quality tears. This can happen for a number
of reasons, including aging, hormonal changes in women and side effects of diseases or
medications.
It is now possible to objectively measure the degree of dry eye disease by collecting a tiny
sample of tears from the corner of the eye and then measuring the amount of salt in the tears
(termed osmolarity). We aim to establish the overall levels of raised and normal tear
osmolarity in people presenting to the eye clinic with complaints of dry eye, and relate this
to other factors such as symptoms, topical and nutritional medication and dry eye treatment.
This study will investigate the efficacy of two treatment non-pharmaceutical therapies (tear drop alone, tear drop combined with omega 3 nutritional supplement and warm compresses) for dry eye reporting patients against a control (saline) over a 3 month period. A relatively new clinical measure (osmolarity) will be performed alongside traditional tear film volume, tear film stability, gland integrity and ocular surface damage measures to determine how this influences symptomatic complaints. ;
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