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NCT02298881 Clinical Trial

Ocular Surface Microbiome

Dry Eye Syndromes Clinical Trial

Official title:
Diversity and Dynamic Stability of the Ocular Surface Microbiome

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02298881
Other study ID # 43018
Secondary ID 1R01EY022038-01A
Status Completed
Phase
First received
Last updated
Start date July 2013
Est. completion date May 1, 2021

Study information
Verified date May 2021
Source University of Washington
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to collect samples from the surface of eyelids to try to grow and identify bacteria or fungus that might be present, and to try to understand why people have dry eye symptoms.

Description:

"Dry eye" is a very common eye condition, which may or may not be caused by specific microorganisms that live on the surface of the eye. In this study, a combination of tissue culture and molecular biology techniques will be used to identify every microbe (bacteria, fungus, or virus) on the surface of eyes of people with dry eye syndrome, as well as a 'control' group of people who don't have dry eye disease.

Recruitment information / eligibility
Status Completed
Enrollment 80
Est. completion date May 1, 2021
Est. primary completion date May 1, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Subjects with ocular surface discomfort with an Ocular Surface Disease Index score of greater than 60 - Subjects with and Ocular Surface disease Index score less than 30 - Males and females age 18 or older Exclusion Criteria: - Contact lens wear - Use of oral or topical antibiotics in past 6 months - Use of prescription eye medication in past 6 months - Penetrating ocular or keratoplasty surgery in last 12 months - Children under the age of 18

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States UW Medicine Eye Institute Seattle Washington

Sponsors (3)
Lead Sponsor Collaborator
University of Washington National Eye Institute (NEI), National Institutes of Health (NIH)

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary To catalog the bacteria and other micro-organisms that are naturally found on the eye surface. 6 months
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