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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT00405457 Completed - Dry Eye Clinical Trials

Efficacy and Safety of a New Multi-dose Lubricant Eye Drop Concomitant With Restasis® (Cyclosporine A) for the Treatment of Dry Eye Symptoms

Start date: November 2006
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy, safety and tolerability of a combination of Optive® Artificial Tears with Restasis®.The primary hypothesis is that the Ocular Surface Disease Index (OSDI) score and symptoms will be the same or lower than baseline after treatment in these patients. The patients will tolerate the combination of Restasis® and Optive® with a low incidence of clinical adverse events.

NCT ID: NCT00404131 Completed - Dry Eye Disease Clinical Trials

Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease

Start date: March 2001
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to compare the effectiveness and safety of INS365 Ophthalmic Solution with placebo when applied topically in subjects with dry eye disease.

NCT ID: NCT00403975 Completed - Dry Eye Disease Clinical Trials

Study of Diquafosol Tetrasodium Ophthalmic Solution in Subjects With Dry Eye Disease

Start date: June 2004
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to assess the effectiveness and safety of 2% diquafosol tetrasodium ophthalmic solution versus placebo following 6 weeks of treatment in subjects with mild to moderate dry eye disease.

NCT ID: NCT00403715 Completed - Dry Eye Disease Clinical Trials

Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease

Start date: February 2001
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to compare the effectiveness and safety of INS365 Ophthalmic Solution with Placebo when applied topically in subjects with dry eye disease.

NCT ID: NCT00399061 Completed - Dry Eye Clinical Trials

Efficacy of Optive Versus Systane Concomitant With Restasis (Cyclosporine A) for the Treatment of Dry Eye Symptoms

Start date: November 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy of Optive versus Systane used concomitantly with topical cyclosporine for the treatment of dry eye.

NCT ID: NCT00388791 Completed - Dry Eye Clinical Trials

Comparison of Systane Free vs. Saline in the Treatment of Dry Eye

Start date: October 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficacy of Systane Free to Saline in decreasing the symptoms of dry eye after aggressive therapy. As a principal outcome measure, we are using the modified Schein dry eye symptomatology questionaire to determine whether any improvement in signs is mirrored by improvement in the Schein Score. Up to 30 dry eye subjects will be dosed six times per day for one month. The typical clinical signs will be onmitored (e.g., corneal staining) along with dyrness symptoms. The hypothesis is that an optimized drop, Systane Free, will be more effective than saline solution in improving dry eye signs and symptoms.

NCT ID: NCT00386646 Completed - Dry Eye Syndromes Clinical Trials

Comparative Study of 0.5% Carboxymethylcellulose With 0.005% Stabilized Oxychlorocomplex (PURITEā„¢) Versus 0.5% Carboxymethylcellulose in the Treatment of Dry Eye

Start date: February 2004
Phase: Phase 4
Study type: Interventional

To compare if 0.5% carboxymethylcellulose with 0.005% SOC (Stabilized oxychloro complex) have the same effectiveness and safety as 0.5% carboxymethylcellulose on dry eye patients.

NCT ID: NCT00372034 Completed - Dry Eye Syndromes Clinical Trials

The Effect of Punctal Plugs on Tear Volume and Osmolality

Start date: July 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the role of tear volume in discomfort and dryness sensations during contact lens wear, and the possible influence on osmolality and ocular surface sensitivity.

NCT ID: NCT00370747 Completed - Dry Eye Syndromes Clinical Trials

Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome

Start date: September 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether ecabet ophthalmic solution is an effective treatment for dry eye syndrome

NCT ID: NCT00357201 Completed - Dry Eye Syndromes Clinical Trials

Efficacy of T1675 Versus Placebo in Patients With Bilateral Treated Moderate Dry Eye Syndrome

Start date: November 2004
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy of a 6-month (± 14 days) dietary supplementation period with T1675, a per os omega 3 and omega 6 polyunsaturated essential fatty acid dietary formulation, versus placebo in patients with bilateral treated moderate dry eye syndrome