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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT00667004 Completed - Dry Eye Disease Clinical Trials

Efficacy Study of Ecabet Ophthalmic Solution in Dry Eye Disease

Start date: March 22, 2008
Phase: Phase 2
Study type: Interventional

Efficacy study of ecabet ophthalmic solution in dry eye disease

NCT ID: NCT00620893 Completed - Dry Eye Syndromes Clinical Trials

Bilateral, Masked Comparison of PEG-400 Based Artificial Tear vs. Systane for Dry Eye Signs, Symptoms & Refractive Regression Associated With Myopic Laser in Situ Keratomilieusis (LASIK).

Start date: February 2008
Phase: Phase 4
Study type: Interventional

This study will evaluate and compare 2 artificial tears in their ability to reduce post LASIK dry eye signs and symptoms. The secondary endpoint of this study is to evaluate refractive regression in these patients. The 'Refractive Outcome' data point will be defined as the difference between the post-op spherical equivalent (SE) and the pre-op targeted SE.

NCT ID: NCT00611403 Completed - Dry Eye Syndromes Clinical Trials

Safety and Efficacy Study of Cyclosporine Ophthalmic Emulsion in Post-LASIK Patients

Start date: December 2007
Phase: Phase 2
Study type: Interventional

This study will evaluate the safety and efficacy of cyclosporine ophthalmic emulsion administered twice daily following LASIK surgery

NCT ID: NCT00610480 Completed - Dry Eye Disease Clinical Trials

Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops

Start date: November 2007
Phase: N/A
Study type: Interventional

The goal of this research is to evaluate and compare the effectiveness of Systane® versus Optiveā„¢ on aqueous tear film stability in patients with a diagnosis of Dry Eye Syndrome and to determine the possible application for this product in the future. Systane® is marketed as over-the-counter tear lubricating therapy in the United States under the FDA monograph.

NCT ID: NCT00607776 Completed - Dry Eye Clinical Trials

Artificial Tears Study in Mild to Moderate Dry Eye Patients

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The mean change in the subjective comfort score from baseline of the test group is at least 2.0 units less than that of the control group.

NCT ID: NCT00600288 Completed - Dry Eye Disease Clinical Trials

Study of the Effect of Diquafosol Tetrasodium Ophthalmic Solution, 2% Versus Placebo in Dry Eye Subjects (P08634)

Start date: January 2008
Phase: Phase 3
Study type: Interventional

The purpose of this pilot study is to evaluate the effect of diquafosol tetrasodium Ophthalmic Solution, 2% in dry eye subjects.

NCT ID: NCT00599716 Completed - Dry Eye Disease Clinical Trials

Safety and Efficacy Assessment of Vismed® (Sodium Hyaluronate) for the Treatment of Dry Eye Syndrome

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The study is designed to assess the safety and efficacy of Vismed®, a special eye drop containing sodium hyaluronate, in the treatment of dry eye syndrome. Vismed® is being compared to another eye drop, identical in composition except that it does not contain the active ingredient, sodium hyaluronate. This eye drop is designed as the "vehicle." Some subjects are to receive Vismed® treatment, while others are to receive the vehicle; the assignment of subjects to receive either Vismed or vehicle is to be random. The two-week treatment phase is followed by a one week follow-up period to evaluate safety of Vismed®.

NCT ID: NCT00567177 Completed - Clinical trials for Treatment of Dry Eye Disease

Objective Measurements of Prolonged Effects of Restasis on Dry Eye Disease

Start date: November 2007
Phase: Phase 4
Study type: Interventional

We propose to investigate the response to Restasis, over a prolonged period of time in heavy computer users with dry eye disease.

NCT ID: NCT00565669 Completed - Dry Eye Syndrome Clinical Trials

Evaluation of Blink Tears and Systane Concomitant With Restasis for the Treatment of Dry Eye Symptoms

Start date: October 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of Blink Tears and Systane used concomitantly with topical cyclosporine for the treatment of dry eye.

NCT ID: NCT00560638 Completed - Dry Eye Clinical Trials

Loteprednol Etabonate Opthalmic Suspension for the Treatment of Dry Eye

Start date: November 2005
Phase: Phase 2
Study type: Interventional

This was a single-center, randomized, double-masked, placebo-controlled, parallel-group, 4-visit, CAE (Controlled Adverse Environment) study lasting approximately 4 weeks. Subjects were randomized to receive loteprednol etabonate ophthalmic suspension, 0.5% or placebo (vehicle of loteprednol etabonate ophthalmic suspension, 0.5%) and instructed to dose bilaterally either TID or QID according to randomization.