Dry Eye Syndrome Clinical Trial
Official title:
Effects of Conventional Dry Eye Treatments on the Ocular Surface Response to Low Humidity Environment in Patients With Keratoconjunctivitis Sicca.
The purpose of this study is to evaluate whether, in people with dry eye syndrome, over the
counter artificial tears and the prescription eye drop, dexamethasone, change or effect the
eyes response to a low humidity environment.
It is known that irritation from dry eye can be improved by over the counter artificial tears
because they wet and lubricate the eyes. The prescription eye drop, dexamethasone, can also
improve eye irritation by decreasing the inflammation that develops in dry eye. Thus, the
investigators hypothesize that the use of these conventional dry eye treatments will improve
the eyes' response to a low humidity environment.
This study evaluated the effects of the corticosteroid dexamethasone on suppressing development of eye irritation, cornea epithelial disease and increased production of inflammatory mediators in subjects who were subjected to an experimental low humidity drafty environment. ;
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