Effects of Dry Eye Treatments on the Ocular Surface

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate whether, in people with dry eye syndrome, over the counter artificial tears and the prescription eye drop, dexamethasone, change or effect the eyes response to a low humidity environment.

It is known that irritation from dry eye can be improved by over the counter artificial tears because they wet and lubricate the eyes. The prescription eye drop, dexamethasone, can also improve eye irritation by decreasing the inflammation that develops in dry eye. Thus, the investigators hypothesize that the use of these conventional dry eye treatments will improve the eyes' response to a low humidity environment.

Clinical Trial Description

This study evaluated the effects of the corticosteroid dexamethasone on suppressing development of eye irritation, cornea epithelial disease and increased production of inflammatory mediators in subjects who were subjected to an experimental low humidity drafty environment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01797822
Study type	Interventional
Source	Baylor College of Medicine
Contact
Status	Completed
Phase	Phase 4
Start date	February 2013
Completion date	December 2015

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