Dry Eye Under China's Dynamic COVID-zero Strategy

Dry Eye Symptoms Clinical Trial

Official title:

Dry Eye Symptoms of University Students Under China's Dynamic COVID-zero Strategy: A Comparison Between the Epidemic and Non-epidemic Areas

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05476068
• Other study ID #: [2022]NO.(001).
• Status: Completed
• Start date: March 20, 2022
• Est. completion date: May 25, 2022

Study information

• Verified date: July 2022
• Source: Second Affiliated Hospital of Nanchang University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To compare the prevalence of dry eye symptoms and to investigate the association of the risk factors with the dry eye symptomatology among university students in the epidemic and non-epidemic areas of China under the COVID-zero strategy.

Description:

As the COVID-19 outbreak at the end of 2019 spread around the world, the World Health Organization declared it a public health emergency of international concern on 30th January, and a global pandemic on 1st March. In addition to the threat of coronavirus itself, anti-epidemic measures such as wearing masks, maintaining social distance, prohibiting group gathering, blockade, isolation, curfew, closure, working at home, online learning, etc., have also greatly changed people's daily life dynamics. Unlike the previous regional blockade (city-wide) suspension of school and work, China has shifted to dynamic prevention and control in April 2020, and the basic life and activities in the epidemic area are not restricted. This study aims to compare the prevalence of dry eye symptoms and to investigate the association of the risk factors with dry eye symptoms among college students in the epidemic and non-epidemic areas of China under the dynamic COVID-zero strategy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1807
• Est. completion date: May 25, 2022
• Est. primary completion date: May 20, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 45 Years

Eligibility

Inclusion criteria:

• College students with age =18 years

• No other medication history in recent 2 weeks;

• Have high compliance and are willing to fill in the questionnaire on time

Exclusion criteria:

• routinely using artificial tears and Other eye drops;

• taking any medication that could interfere with the results of the study;

• with any history of eye surgery

Related Conditions & MeSH terms

• Dry Eye Symptoms
• Dry Eye Syndromes
• Keratoconjunctivitis Sicca

Locations

Country	Name	City	State
China	The Second Affiliated Hospital of Nanchang University	Nanchang	Jiangxi

Sponsors (1)

Lead Sponsor	Collaborator
Yifeng Yu

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	A score of ocular surface disease index (OSDI)questionnaire	Ocular surface disease index (OSDI)questionnaire : (1) OSDI: =12 (no DED symptoms), 13 = d = 22 (mild DED symptoms), 23 = d = 32 (moderate DED symptoms), and =33 (severe DED symptoms).	DAY 0
Primary	A score of GAD-7 questionnaire	GAD-7 questionnaire: (1) 0 < GAD-7 = 4 (normal), 5 = GAD-7 = 9 (mild anxiety), 10 = GAD-7 = 13 (moderate anxiety), 14 = GAD-7 = 18 (moderate and severe anxiety), and 19 = GAD-7 = 21 (severe anxiety).	DAY 0
Primary	A score of PHQ-9 questionnaire	PHQ-9 questionnaire: (1) 0 < PHQ-9 = 4 (normal), 5 = GAD-7 = 9 (mild depression), 10 = GAD-7 = 14 (moderate depression), 15 = GAD-7 = 19 (moderate and severe depression), and 20 = GAD-7 = 27 (severe depression).	DAY 0
Secondary	A score of UCLA Loneliness Scale questionnaire	UCLA Loneliness Scale Questionnaire: (1) UCLA < 28 (low loneliness), 28 = UCLA = 33 (generally lower), 33 < UCLA = 39 (intermediate level), 39 < UCLA = 44 (generally higher), and GAD-7 > 44 (highly lonely).	DAY 0
Secondary	Students' increased use of mobile phones	Students choose to increase the time of using mobile phones according to options: 0 hours, less than 1 hour, 1-3 hours, 3-5 hours, 5-7 hours, and more than 7 hours	DAY 0
Secondary	Frequency of student sports	Students choose the frequency of sports according to the options, which are: less than once a month, 2-3 times a month, 1-2 times a week, 3-5 times a week, and once a day.	DAY 0