Ocular Surface Immune Response in Dry Eye Disease

Status Completed

Clinical Trial Summary

In vivo confocal microscopy (IVCM) is a sensitive imaging tool for detecting dry eye-associated subclinical inflammation. Studies have previously shown that IVCM provides an in vivo metric to measure inflammatory changes in the central cornea. The objective of the current study is to assess inflammatory response changes in the peripheral cornea and the conjunctiva by analyzing epithelial immune cell density and morphology in these areas and then correlating the IVCM findings to clinical signs and symptoms to establish novel objective imaging biomarkers.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02042820
Study type	Observational
Source	Tufts Medical Center
Contact
Status	Completed
Phase	N/A
Start date	January 2014
Completion date	July 2015

View Details

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