Clinical trial NCT00294593 - References

Down Syndrome — Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome

Citation(s)

•   Botez MI, Botez T, Leveille J, Bielmann P, Cadotte M
  Neuropsychological correlates of folic acid deficiency: facts and hypotheses. In: Botez MI, Reynolds EH, eds. Folic acid in neurology, psychiatry and internal medicine. New York, Raven Press, 1979:435-461.
•   Lejeune J
  [Pathogenesis of mental impairment in trisomy 21]. Ann Genet. 1991;34(2):55-64. Review. French.

One-year Double-blind Placebo-controlled Phase 2-3 Study to Evaluate the Effect of Oral Folinic Acid Treatment (1mg/kg/d) on the Psychomotor Development of Young Down Syndrome Patients

Details for clinical trial NCT00294593