Dilatation and Evacuation Clinical Trial
Official title:
Prophylactic Lidocaine Spray for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation
To examine whether application of lidocaine spray in cervical preparation for second
trimester dilatation and evacuation alleviates pain and is superior to current protocol of
preparation without analgesia and superior to placebo.
a double- blind, randomized, placebo- controlled trial, performed at a single tertiary
medical center. Eligible participants aged 18 and older and about to undergo dilation &
evacuation of the uterus between 12 to 24 weeks of gestation. Participants will be randomized
using computer generated allocation to receive 10% Xylocaine (lidocaine group) spray or
normal saline 0.9% (placebo group), applied identically topically to the endocervix and
ectocervix before laminaria insertion. The primary outcome will be the participant's reported
pain score immediately after the first laminaria was inserted as measured on a 10 cm visual
analog scale (VAS). Secondary outcomes wiil be reported pain scores at speculum removal, 15
minutes after speculum insertion and immediately before the D&E procedure.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT05579288 -
Use of Nitrous Oxide for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Dilatation and Evacuation
|
Early Phase 1 |