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Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms Clinical Trial

Official title:
A Clinical Study to Assess the Safety, Feasibility, and Efficacy of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms

Clinical Trial Summary

The purpose of this study is to assess the safety, feasibility, and efficacy of personalized mRNA vaccine iNeo-Vac-R01 alone in subjects with advanced digestive system neoplasms.

Clinical Trial Description

This is a multi-part single-center, open-label, single-arm clinical study of personalized mRNA vaccine iNeo-Vac-R01 monotherapy in subjects with advanced digestive system neoplasms. The study will include a dose escalation phase and dose expansion phase. The traditional 3+3 design will be used in dose escalation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06019702
Study type Interventional
Source Sir Run Run Shaw Hospital
Contact Xiujun Cai, MD
Phone 0086-0571-86006605
Email caixiujunzju@yahoo.com.cn
Status Recruiting
Phase Phase 1
Start date September 8, 2023
Completion date December 31, 2027
View Details
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