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Diffuse B-Cell Lymphoma clinical trials

View clinical trials related to Diffuse B-Cell Lymphoma.

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NCT ID: NCT03283202 Completed - Clinical trials for Diffuse B-Cell Lymphoma

Study of Safety and Efficacy of Avadomide (CC-122) Combined With RCHOP for Newly-diagnosed DLBCL With Poor Risk Factors

Start date: October 4, 2017
Phase: Phase 1
Study type: Interventional

This is Phase 1/2 study of avadomide (CC-122) in combination with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy, for first-line treatment of patients with Diffuse B-Cell Large B-Cell Lymphoma (DLBCL) that has poor risk factors. Approximately 40% of patients diagnosed with DLBCL are not cured with R-CHOP alone and would need additional treatment for DLBCL in the future. The addition of the experimental drug avadomide (CC-122) with R-CHOP could help in controlling DLBCL in this patient population.