Specific Carbohydrate Diet for Clostridium Difficile — SCD_cDiff  

Diet Modification Clinical Trial

Official title: Treatment With the Specific Carbohydrate Diet for Children With Clostridium Difficile Colonization

Status Completed

Clinical Trial Summary

The investigators are doing this research study to answer questions about a nutritional therapy called the Specific Carbohydrate Diet (SCD) for children with active Clostridium Difficile Infection.

For this study, the investigators will be looking to determine:

1. Is SCD effective for the treatment for Clostridium Difficile Colonization?

2. Is the SCD well tolerated?

Clinical Trial Description

The aim of this study is to determine the tolerability and potential efficacy of dietary therapy, the Specific Carbohydrate Diet (SCD), in pediatric patients with persistent antigen positivity due to C. difficile colonization with minimally active symptomatology. The goal of this pilot study is to gather preliminary data for a future treatment controlled trial of SCD versus standard medical therapy.

This is a single center, open labelled study designed to determine tolerability, preliminary safety and potential efficacy in pediatric patients with persistent C. difficile colonization with minimally active symptomatology. The study patients will be recruited from Seattle Children's Gastroenterology and Infectious Disease clinic. ;

Related Conditions & MeSH terms

• Clostridium Difficile Infection
• Clostridium Infections
• Diet Modification

• NCT number: NCT03925636
• Study type: Interventional
• Source: Seattle Children's Hospital
• Status: Completed
• Phase: N/A
• Start date: June 8, 2016
• Completion date: March 1, 2022