Health Impact Study of Aquatabs in Tamale, Ghana

Diarrhea Clinical Trial

Official title:

Health Impact Study of a Water Treatment Tablet, Aquatabs, in Tamale, Ghana

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00252928
• Other study ID #: CDC-NCID-4730
• Status: Completed
• Phase: N/A
• First received: November 10, 2005
• Last updated: October 29, 2007
• Start date: July 2006
• Est. completion date: November 2006

Study information

• Verified date: October 2007
• Source: Centers for Disease Control and Prevention
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal GovernmentGhana: University for Development Studies
• Study type: Interventional

Clinical Trial Summary

The purpose of this study to determine whether Aquatabs, a water treatment tablet, reduces diarrheal diseases in a peri-urban population of Tamale, Ghana.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 240
• Est. completion date: November 2006
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Households with at least one child under 5 years old

Exclusion Criteria:

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Diarrhea

Intervention

Other:
• Sodium dichloroisocyanurate (NaDCC) tablets
Intervention arm receives NaDCC tablets to use for to disinfect their household water for use for 20L of water. Ideally, disinfection occurs every day.
• Placebo
Placebo

Locations

Country	Name	City	State
Ghana	NewEnergy	Tamale
Ghana	University of Development Studies	Tamale
United States	Emory University Center for Global Safe Water	Atlanta	Georgia

Sponsors (5)

Lead Sponsor	Collaborator
Centers for Disease Control and Prevention	Emory University Center for Global Safe Water, Medentech, NewEnergy, University for Development Studies, Tamale, Ghana

Countries where clinical trial is conducted

United States,  Ghana, 

References & Publications (5)

Mintz ED, Reiff FM, Tauxe RV. Safe water treatment and storage in the home. A practical new strategy to prevent waterborne disease. JAMA. 1995 Mar 22-29;273(12):948-53. Review. — View Citation

Quick RE, Venczel LV, González O, Mintz ED, Highsmith AK, Espada A, Damiani E, Bean NH, De Hannover EH, Tauxe RV. Narrow-mouthed water storage vessels and in situ chlorination in a Bolivian community: a simple method to improve drinking water quality. Am J Trop Med Hyg. 1996 May;54(5):511-6. — View Citation

Quick RE, Venczel LV, Mintz ED, Soleto L, Aparicio J, Gironaz M, Hutwagner L, Greene K, Bopp C, Maloney K, Chavez D, Sobsey M, Tauxe RV. Diarrhoea prevention in Bolivia through point-of-use water treatment and safe storage: a promising new strategy. Epidemiol Infect. 1999 Feb;122(1):83-90. — View Citation

Reiff FM, Roses M, Venczel L, Quick R, Witt VM. Low-cost safe water for the world: a practical interim solution. J Public Health Policy. 1996;17(4):389-408. — View Citation

Sobel J, Mahon B, Mendoza CE, Passaro D, Cano F, Baier K, Racioppi F, Hutwagner L, Mintz E. Reduction of fecal contamination of street-vended beverages in Guatemala by a simple system for water purification and storage, handwashing, and beverage storage. Am J Trop Med Hyg. 1998 Sep;59(3):380-7. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Measure the impact of Aquatabs on diarrhea among persons in households in Tamale, Ghana.		12 weeks
Secondary	Assess the microbiological quality of household water among persons living in Tamale, Ghana.		12 weeks
Secondary	Determine the acceptability of Aquatabs.		12 weeks

External Links

•   Centers for Disease Control and Prevention: Safe Water System
•   World Health Organization: Global Water Supply and Sanitation Assessment 2000 Report