Diagnostic Imaging Clinical Trial
Official title:
Comparison of PET/CT vs. PET/MRI
| Verified date | April 2021 |
| Source | Stanford University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
This clinical trial studies how well positron emission tomography (PET)/computed tomography (CT) works compared to PET/magnetic resonance imaging (MRI) in evaluating patients with cancer. PET/CT and PET/MRI may determine which scanner is best for the patient's type of cancer and other types of cancers.
| Status | Completed |
| Enrollment | 53 |
| Est. completion date | February 5, 2020 |
| Est. primary completion date | November 30, 2016 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | INCLUSION CRITERIA - Cancer diagnosis - Capable of complying with study procedures - Able to remain still for duration of imaging procedure (approximately 90 minutes total) - Written informed consent EXCLUSION CRITERIA - Pregnant or nursing - Metallic implants - Impaired renal function |
| Country | Name | City | State |
|---|---|---|---|
| United States | Stanford University, School of Medicine | Palo Alto | California |
| Lead Sponsor | Collaborator |
|---|---|
| Stanford University |
United States,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Absolute Accuracy of SUV Max of PET/CT vs PET/MRI | Standardized uptake value max (SUVmax) is a measurement of the maximum radiopharmaceutical uptake value within the region of interest (ROI). SUVmax is calculated as the ratio of activity concentration:injected dose/body weight. The outcome is reported as the mean SUVmax with standard deviation (SD), reported for 8 specific organs or bodily locations. | 4 hours | |
| Secondary | PET/CT vs PET/MRI Difference in Standardized Uptake Value Max (SUVmax), by Radiotracer | Standardized uptake value max (SUVmax) is a measurement of the maximum radiopharmaceutical uptake within the region of interest (ROI). Relative accuracy of a particular radiotracer in a particular tissue is determined by expressing the absolute accuracy (obtained in the primary outcome measure) in terms of percent difference between SUVmax values obtained from PET/CT and PET/MR.
Percentage difference is expressed as the difference of the means in SUVmax for the PET/CT and PET/MRI scan procedures for the particular radiotracer, divided by the mean between the values for the 2 scan procedures. The closer the percent difference is to 0%, the better the agreement between the two scanners. The outcome is expressed as the percentage difference, a number without dispersion. |
estimated average of 2 hours |
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