Diabetic Neuropathy Clinical Trial
Official title:
The Evaluation of Safety and Efficacy of JWHGWT on Diabetic Neuropathy
In order to provide a alternative treatment for relieving the pain and numbness of Diabetes Mellitus patients,Traditional Chinese Medicine powder was tested by subjective questionnaire and objective nerve conduction velocity study. Liver and kidney functions were tested to provided safety profiles.
120 participants with diabetic neuropathy were screened in endocrine and metabolism clinics
of Taichung Veterans General Hospital and Chinese Medical University Hospital . Subjects
were randomly distributed into a double-blind, 12 weeks, placebo-controlled procedure.
Subjects were measured by MNSI, SF-BPI, SF-36, SF -MCQ, NCV, AC sugar, HbA1c, lipid
profiles, liver and kidney functions.
Safety evaluations including GPT and creatinine revealed no deterioration after treatment.
Several domains in MNSI, SF-BPI, SF-36, SF -MPQ questionnaires revealed significant
improvements. F-wave in peroneal, tibial nerves and distal latency in tibial nerve in
objective nerve conduction studies revealed significant improvements.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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