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Clinical Trial Summary

Diabetic kidney disease (DKD) is the leading cause for renal replacement therapy in developed country. DKD is also the primary cause of ESKD among middle-aged and elderly people in China. Renal pathological markers have been proved to have clinical and prognostic value in both non diabetic and diabetic kidney diseases. To discriminate lesions by various degrees of severity, the Working Group of the Renal Pathology Society (RPS) developed a pathologic classification for DKD in 2010. The classification is based on glomerular lesions, with a separate evaluation for interstitial and vascular lesions. In a decade, there were several new characteristics common to DKD, such as the presence of mesangiolysis, glomerular hyalinosis, segmental sclerosis and extracapillary hypercellularity, which have been noted in patients with diabetes and may have prognostic importance. But it is still unclear whether thickening of Bowman's capsule predicts the progression of DKD.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06049550
Study type Observational
Source RenJi Hospital
Contact Jiayue Lu
Phone 86-21-34506332
Email royalkeane@hotmail.com
Status Not yet recruiting
Phase
Start date October 1, 2023
Completion date October 31, 2023

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