Use of Insulin Glargine to Treat Diabetic Ketoacidosis

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the effects of the addition of insulin glargine during the early phase of moderate to severe Diabetic Ketoacidosis (DKA) in children.

The investigators hypothesize that the addition of insulin glargine during the early phase of management of DKA will accelerate acidosis correction, decrease the length of insulin infusion, and decrease the total intensive care unit time in children admitted to the ICU.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00179127
Study type	Interventional
Source	Vanderbilt University Medical Center
Contact
Status	Completed
Phase	N/A
Start date	August 2004
Completion date	September 2012

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT05649891` - Checklists Resuscitation Emergency Department	N/A
Completed	`NCT03660189` - Two Bag System for Diabetic Ketoacidosis	N/A
Terminated	`NCT03066440` - Double Blinded Randomized Control Trial of Types of IVF in Children With DKA	Phase 4
Completed	`NCT04940897` - Use of Blood Ketone Meters to Improve Ambulance Hyperglycaemia Care	N/A
Completed	`NCT02930044` - Early Subcutaneous Insulin Glargine Plus Standard of Care for Treatment of Diabetic Ketoacidosis	N/A
Completed	`NCT04926740` - Intravenous Fluids in Adults With Diabetic Ketoacidosis in the Emergency Department	N/A
Terminated	`NCT04567225` - Early Basal Insulin Administration in Adult Diabetic Ketoacidosis Management	Phase 4
Completed	`NCT04017221` - Safety of Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes
Recruiting	`NCT03717896` - Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis	Phase 2
Terminated	`NCT02548494` - Early Administration of Long-acting Insulin Treatment of Diabetic Ketoacidosis in Pediatric Type 1 Diabetes	N/A
Completed	`NCT02006342` - Effectiveness of Subcutaneous Glargine On The Time To Closure of The Anion Gap in Patients Presenting to the Emergency Department With Diabetic Keto-acidosis	N/A
Completed	`NCT01753921` - Evaluation of a Non-invasive Brain Compliance Measurement Device
Completed	`NCT01365793` - Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis	Phase 3
Completed	`NCT00426413` - Ketosis Prone Diabetes in African-Americans	N/A
Not yet recruiting	`NCT05867797` - Risk Factors and Outcomes of Acute Kidney Injury in Patients With Diabetic Ketoacidosis at Sohag University Hospital.
Terminated	`NCT04234867` - Study to Explore the Effect of Dapagliflozin and Stress in Adolescent and Adult Subjects With Type 1 Diabetes (T1D)	Phase 1
Not yet recruiting	`NCT05752279` - Balanced Multi-Electrolyte Solution Versus Saline Trial for Diabetic KetoAcidosis	Phase 3
Completed	`NCT04825639` - Identifying Risk Factors for Developing AKI in Sepsis
Recruiting	`NCT05155917` - Concurrent Subcutaneous Basal Insulin and Intravenous Insulin Pump in Hyperglycemic Crisis Patients Under Critical Care	Phase 2
Recruiting	`NCT05383404` - Clinical and Laboratory Parameters Associated With Different Degrees of Dehydration Among Children With Diabetic Ketoacidosis