Diabetic Foot Clinical Trial
Official title:
Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds
The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | April 2024 |
Est. primary completion date | February 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years to 75 Years |
Eligibility | Inclusion Criteria: - Age group 20-75 years. - Patients with diabetic foot wounds who are scheduled for skin grafting. Exclusion Criteria: - Age <20 years or > 75 years. - An obvious septicemia. - Foot osteomyelitis. - Ulcer resulting from venous insufficiency. - Features of malignant ulcer. - Patients being treated with corticosteroids, immunosuppressive drugs. - Any other serious pre-existing cardiovascular, pulmonary or immunological disease. |
Country | Name | City | State |
---|---|---|---|
Egypt | Sohag university hospital | Sohag |
Lead Sponsor | Collaborator |
---|---|
Sohag University |
Egypt,
Ali Z, Anjum A, Khurshid L, Ahad H, Maajid S, Dhar SA. Evaluation of low-cost custom made VAC therapy compared with conventional wound dressings in the treatment of non-healing lower limb ulcers in lower socio-economic group patients of Kashmir valley. J Orthop Surg Res. 2015 Dec 10;10:183. doi: 10.1186/s13018-015-0314-5. — View Citation
Lone AM, Zaroo MI, Laway BA, Pala NA, Bashir SA, Rasool A. Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case-control study. Diabet Foot Ankle. 2014 Apr 8;5. doi: 10.3402/dfa.v5.23345. eCollection 2014. — View Citation
Ravari H, Modaghegh MH, Kazemzadeh GH, Johari HG, Vatanchi AM, Sangaki A, Shahrodi MV. Comparision of vacuum-asisted closure and moist wound dressing in the treatment of diabetic foot ulcers. J Cutan Aesthet Surg. 2013 Jan;6(1):17-20. doi: 10.4103/0974-2077.110091. — View Citation
Sinha K, Chauhan VD, Maheshwari R, Chauhan N, Rajan M, Agrawal A. Vacuum Assisted Closure Therapy versus Standard Wound Therapy for Open Musculoskeletal Injuries. Adv Orthop. 2013;2013:245940. doi: 10.1155/2013/245940. Epub 2013 Jun 26. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Period of hospitalization. | Number of days of patient hospitalization before and after grafting | 2 weeks | |
Primary | Time of complete healing | Number of days needed for each patient for complete healing after operation | 1 month | |
Primary | Functional outcome | Number of patients with full range of mobility at site of graft Vs number of patients with limited mobility | 5 months | |
Primary | Patient satisfaction of aesthetic outcome | Number of patients satisfied with the aesthetic result of the operation on a scale of 0-10 | 5 months |
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