PRG Combined With Autologous BMMSCs for Treatment of Diabetic Foot Ulcer

Status Recruiting

Clinical Trial Summary

To investigate the treatment effect between Traditional treatment and transplantation of autologous PRG combined with autologous BMMSCs for treatment of diabetic foot ulcer.

Clinical Trial Description

60 diabetic foot ulcer in our hospital will divide into 3 groups: group A (20 diabetic foot ulcer who give Traditional treatment), group B (20 diabetic foot ulcer who give Traditional treatment and transplantation of autologous platelet rich gel)，group C (20 diabetic foot ulcer who give Traditional treatment and transplantation of autologous platelet rich gel combined with autologous bone marrow mesenchymal stem cells). The age, height, weight, blood glucose, glycosylated hemoglobin A1c（HbA1c）, lipid, blood pressure, course of disease, Wound healing rate,transcutaneous oxygen pressure,Amputation rate,Hospital stay will record respectively. And High-sensitive C-reactive protein (HsCRP) and Tumor necrosis factor-α（TNF-α） will detect as Baseline. After each group's treatment, Change from baseline of all indexes will record, one way Analysis of Variance will be analyzed the significantion among 3 groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03248466
Study type	Interventional
Source	Third Military Medical University
Contact
Status	Recruiting
Phase	Early Phase 1
Start date	August 30, 2017
Completion date	July 1, 2020

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