The Relationship Between Arsenic Methylation Capability and Blood Metals in Children With Developmental Delays

Developmental Delays Clinical Trial

Official title:
The Relationship Between Genetic Polymorphism of Arsenic Methylation Enzymes, Arsenic Methylation Capability and Blood Metals, and Developmental Delays in Preschool Children

Status Completed

Clinical Trial Summary

The purpose of this study is to explore the relationship between arsenic methylation and blood metals in children with developmental delays and its correlation with health related quality of life.

Clinical Trial Description

The investigators recruited children with developmental delays and children with normal development from Shin-Kong Ho-Su Memorial Hospital as controls. Information obtained from the interview included socioeconomic and basic demographic characteristics as well as children function, health condition, and quality of life. On the other hand, blood and urine samples of the participants were collected for the analysis of arsenic methylation related enzymes using polymerase chain reaction and restriction fragment length polymorphism. 2 ml blood were digested for the determination of mercury, lead and arsenic. The relationship between arsenic methylation and blood metals in children with developmental delays and its correlation with health related quality of were analyzed. ;

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Developmental Delays

Clinical Trial Details

NCT number	NCT02523989
Study type	Observational [Patient Registry]
Source	Taipei Medical University
Contact
Status	Completed
Phase	N/A
Start date	March 2010
Completion date	July 2011

View Details

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