Desflurane in Children With Laryngeal Mask Airway

Desflurane Anesthesia Clinical Trial

Official title:

Sevoflurane Vs. Sevoflurane-desflurane Anesthesia in Children With Laryngeal Mask Airways; Difference in Respiratory Event, Recovery Time and Emergence Agitation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02470442
• Other study ID #: H-1504-116-668
• Status: Completed
• Phase: N/A
• First received: June 8, 2015
• Last updated: August 2, 2017
• Start date: June 2015
• Est. completion date: March 2016

Study information

• Verified date: August 2017
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to characterize the airway responses to desflurane during maintenance of and emergence from anesthesia in children whose airways were supported with laryngeal mask airways (LMAs).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 200
• Est. completion date: March 2016
• Est. primary completion date: February 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 2 Years to 6 Years

Eligibility

Inclusion Criteria:

• scheduled for elective surgery under general anesthesia with laryngeal mask airway

Exclusion Criteria:

• history of reactive airways disease with an acute exacerbation within the past 2 weeks

• if wheezing or an active upper respiratory infection was present on the day of surgery

• if there was a history of malignant hyperthermia

• a history of moderate-to-severe hepatic dysfunction following anesthesia with desflurane not otherwise explained.

Related Conditions & MeSH terms

• Desflurane Anesthesia

Intervention

Drug:
• Sevoflurane/Desflurane
Anesthesia induced with sevoflurane and anesthetic maintenance with desflurane
• Sevoflurane
Anesthesia induced with sevoflurane and anesthetic maintenance with sevoflurane

Locations

Country	Name	City	State
Korea, Republic of	Seoul national university hospital	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	respiratory adverse events		participants will be followed for postoperative period, an expected average of 30 minutes.
Secondary	emergence agitation		15 minutes after arrival on PACU