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A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis — VALOR  

Dermatomyositis Clinical Trial

Official title:
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Oral Brepocitinib in Adults With Dermatomyositis

Clinical Trial Summary

This is a phase 3, multicenter, randomized, placebo-controlled, double-blind study of treatment with brepocitinib (TYK2/JAK1 inhibitor) in adults with dermatomyositis (DM). The primary objective of this study is to assess the efficacy of two dose levels of brepocitinib in comparison to placebo, as measured by differences in the Total Improvement Score (TIS). After 52 weeks of double-blind treatment, participants have the option to continue therapy in a 52 week open-label extension phase where all participants will receive brepocitinib.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05437263
Study type Interventional
Source Priovant Therapeutics, Inc.
Contact Clinical Trial Administrator
Phone (212) 634-9743
Email ValorStudyManager@PriovantTx.com
Status Recruiting
Phase Phase 3
Start date October 31, 2022
Completion date December 2024
View Details
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