Confocal Raman Spectroscopy: in Vivo Measurement of Physiological Skin Parameters

Dermatologic Disorders Clinical Trial

Official title: Confocal Raman Spectroscopy: in Vivo Measurement of Physiological Skin Parameters - A Pilot Study

Status Completed

Clinical Trial Summary

The purpose of this study is to

I. determine several skin parameters, for example natural moisturizing factor (NMF) and cholesterol, with Raman spectroscopy in vivo and

II. compare the results with the corresponding cholesterol levels measured in venous blood.

Clinical Trial Description

In vivo Raman experiments will be carried out weekly on voluntary participants using a RiverDiagnostics gen2-SCA Skin Composition Analyzer (RiverDiagnostics, Rotterdam, Netherlands). All experiments will be carried out on the volar forearm. Semi-quantitative concentration profiles for several skin parameters will be determined, for example natural moisturizing factor (NMF) and cholesterol.

Additionally the total cholesterol level will be detected by venous blood sample analysis. The blood samples will be taken weekly within two weeks, similar to the Raman measurements. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Dermatologic Disorders
• Disease
• Disorder of Cholesterol Metabolism
• Skin Diseases

• NCT number: NCT02854475
• Study type: Interventional
• Source: University of Vienna
• Status: Completed
• Phase: N/A
• Start date: July 2016
• Completion date: July 2016