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Dermatitis, Atopic clinical trials

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NCT ID: NCT00660127 Completed - Atopic Dermatitis Clinical Trials

The Effect of Visual Stimuli on Itch Perception Intensity in Healthy and Atopic Dermatitis Patients

Start date: October 2007
Phase: N/A
Study type: Observational

The purpose of this research study is to assess whether seeing other people itch affects itch perception in patients with atopic dermatitis and healthy subjects.

NCT ID: NCT00654355 Completed - Atopic Dermatitis Clinical Trials

Measuring Adherence to Topical Therapy in Children With Atopic Dermatitis and the Impact of a Return Visit

Start date: April 2008
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to better understand how the study drug works when people use it to treat atopic dermatitis.

NCT ID: NCT00616538 Completed - Atopic Dermatitis Clinical Trials

Epiceram™ Device Versus Mid-Strength Topical Steroid (Fluticasone Propionate 0.05%) for Treatment of Atopic Dermatitis

Start date: December 2006
Phase: Phase 4
Study type: Interventional

Novel therapies for AD that avoid immunosuppression and potential carcinogensis are needed. EpiCeram™ , a topical cream, represents a novel class of therapy for skin disorders that does not contain corticosteroids or other anti-inflammatory drugs. The objective of the present study is to demonstrate the safety and efficacy of EpiCeram ™ in the treatment of moderate to severe atopic dermatitis as compared to mid-strength topical steroid cream following twice daily dosing for four weeks in pediatric patients with AD. The potential benefit to patients lies in the potential for EpiCeram ™ to provide restoration of the normal skin barrier as shown in previous studies and eliminate or reduce the requirement for supplemental topical steroid administration.

NCT ID: NCT00616096 Completed - Dermatitis, Atopic Clinical Trials

Study of Immunoadsorption to Treat Severe Atopical Dermatitis Associated With Excessively High Serum IgE Levels

Start date: January 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether immunoadsorption is effective in the treatment of severe atopic dermatitis associated with excessively high serum IgE levels.

NCT ID: NCT00614731 Completed - Atopic Dermatitis Clinical Trials

Responses to Immunization With Keyhole Limpet Hemocyanin Administered by Scarification and the Intradermal Route

Start date: December 2007
Phase: Phase 1
Study type: Interventional

Atopic dermatitis (AD) is a skin disorder in which people often have swelling and skin infections. People with this disease cannot receive the smallpox vaccine because it could cause them to have a fatal reaction known as eczema vaccinatum (EV). Keyhole limpet hemocyanin (KLH) is a protein that can be used to deliver vaccines to the body. The purpose of this study is to determine a baseline immune reaction to KLH in people without AD. Once this has been established, other studies can be designed to determine whether KLH can be used to give vaccines to people with AD.

NCT ID: NCT00610142 Completed - Atopic Dermatitis Clinical Trials

Comparison of Atrophogenic Effect of Hydrocortison 1% Cream and Pimecrolimus 1% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHz Ultrasound of Uninvolved Skin in Patients With Atopic Dermatitis

OCT-AD
Start date: December 2007
Phase: Phase 2
Study type: Interventional

to explore the atrophogenic potentials of hydrocortison 1% cream and pimecrolimus 1% cream on unaffected forehead skin

NCT ID: NCT00576238 Completed - Atopic Eczema Clinical Trials

Skin Tolerance Study of Betamethasone Creams in Atopic Eczema and the Preventative Properties of a Moisturiser

Start date: January 2004
Phase: Phase 3
Study type: Interventional

Topical steroid creams as well as moisturizing creams are important parts of the treatment strategy of atopic eczema. This study aims to investigate the tolerance of a new strong steroid cream in comparison to an already marketed reference cream with equal amount of active but with different cream vehicle. The second part of the study will investigate the possible preventative property of a moisturizing cream on skin that has been previously cleared from eczema.

NCT ID: NCT00568412 Completed - Clinical trials for Mild to Moderate Atopic Dermatitis

A Clinical Study in Children and Adolescents With Mild to Moderate Atopic Dermatitis

Start date: December 2007
Phase: Phase 4
Study type: Interventional

To show therapeutic efficacy of Zarzenda cream compared to Elidel cream in children and adolescents with mild to moderate atopic dermatitis

NCT ID: NCT00560378 Completed - Dermatitis, Atopic Clinical Trials

Long-term Safety of Protopic in Atopic Eczema

Start date: June 1998
Phase: Phase 3
Study type: Interventional

Patients who have participated in previous studies with Tacrolimus ointment for atopic eczema are entitled to enter this four-year follow study to investigate the safety of treatment with Tacrolimus ointment 0.1%

NCT ID: NCT00560326 Completed - Dermatitis, Atopic Clinical Trials

Tacrolimus Ointment Long Term Safety in Young Children With Atopic Dermatitis

Start date: June 2003
Phase: Phase 2
Study type: Interventional

The objective of this study is to assess the safety and efficacy of 0.03% tacrolimus ointment as long-term treatment in paediatric patients with atopic dermatitis.