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Dermatitis, Atopic clinical trials

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NCT ID: NCT01053247 Completed - Atopic Dermatitis Clinical Trials

Study of 0416 Ointment in the Treatment of Atopic Dermatitis

Start date: January 2008
Phase: Phase 3
Study type: Interventional

The aim of this trial is to assess the efficacy of 0416 Ointment in the Treatment of Atopic Dermatitis. Treatment medication will be administered as follows: Apply a thin layer of ointment to affected skin areas twice daily and rub in gently and completely. Study medication will be applied twice a day, approximately 12 hours apart, for approximately 2 weeks.

NCT ID: NCT01049243 Completed - Atopic Dermatitis Clinical Trials

A Study Evaluating the Efficacy of Fluocinonide Cream 0.1% (Vanos) in Subjects With Atopic Dermatitis

Vanos
Start date: March 2009
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to better understand how fluocinonide cream 0.1% (Vanos®) works when people use it to treat atopic dermatitis for just a few days.

NCT ID: NCT01037881 Completed - Atopic Dermatitis Clinical Trials

LEO 29102 Cream in the Treatment of Atopic Dermatitis

Start date: December 2009
Phase: Phase 2
Study type: Interventional

This is a proof of concept and dose finding Phase II trial comparing 5 dose strengths with vehicle and an active comparator (Elidel cream 10 mg/g) in a 4 week, twice daily treatment regimen in mild to moderate atopic dermatitis patients.

NCT ID: NCT01033097 Completed - Clinical trials for Pruritus in Patients With Atopic Dermatitis

Safety and Efficacy of DNK333 in Atopic Dermatitis Patients

Start date: November 2009
Phase: Phase 2
Study type: Interventional

This study will assess the safety and efficacy of DNK333 in patients with atopic dermatitis suffering from pruritus, who require systemic treatment of the disease.

NCT ID: NCT01016106 Completed - Atopic Dermatitis Clinical Trials

Genetic Screening for Filaggrin Mutation in Atopic Dermatitis and Ichthyosis Vulgaris in the African American Population

Start date: June 2010
Phase: N/A
Study type: Interventional

The investigators' primary objective is to identify common and rare mutations in the filaggrin gene in African American patients with a diagnosis of atopic dermatitis and ichthyosis vulgaris. Atopic dermatitis, or eczema, is a common, chronic, relapsing and remitting problem in many children and affects 10-20% of the pediatric population. Itch is a predominant feature of this disease and is quite disruptive to daily activities of life. In addition to itch, it is characterized by markedly dry skin, small red bumps that may have fluid. Ichthyosis vulgaris is characterized by extremely dry, scaly skin with a fine white scale and increased amounts of lines noted on the palms. Filaggrin is a protein that is essential for the skin to function properly as a barrier and found to be mutated in some European patients with ichthyosis vulgaris and atopic dermatitis. This association has not been looked at in the African American population. Genomic DNA (gDNA) will be purified from buccal swabs using commercially available kits and analyzed.

NCT ID: NCT01007331 Completed - Atopic Dermatitis Clinical Trials

Probiotic Bacteria to Infants With Atopic Dermatitis

Start date: November 2006
Phase: N/A
Study type: Interventional

The objective of the study is to examine whether 8 weeks intervention with probiotics influence the eczema in infants suffering from Atopic Dermatitis. Furthermore the influence of the immunologic status and the intestinal microflora, inflammation and permeability will be investigated.

NCT ID: NCT01005823 Completed - Atopic Dermatitis Clinical Trials

A Safety, Tolerability and Pharmacokinetic Study of LEO 29102 in Subjects With Atopic Dermatitis

Start date: October 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of 7 days treatment with LEO 29102 in adult patients with atopic dermatitis.

NCT ID: NCT00991198 Completed - Atopic Dermatitis Clinical Trials

The Role of Topically Dissolved Oxygen (TDO) to Ameliorate Signs of Photodamage

Start date: September 2009
Phase: Phase 2
Study type: Interventional

This study is an evaluation of the role of topical dissolved oxygen to lessen visible signs of photodamage using a select regimen of topical dissolved oxygen containing cosmeceutical products. Evaluation of the overall skin tolerability of topical dissolved oxygen (safety) utilizing the regimen of products.

NCT ID: NCT00985894 Completed - Atopic Dermatitis Clinical Trials

Comparison Between Asynchronous Online Care Model With Usual In Office Care for the Management of Atopic Dermatitis

Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if an asynchronous online model of teledermatology can achieve similar clinical outcomes as compared to conventional in-office care for the management of atopic dermatitis. The investigators also aim to determine the effects of this online care model on patient quality of life as well as patient and physician satisfaction. The investigators' hypotheses include the following: 1. Compared to in-person visits, the online care model will result in similar clinical improvement in atopic dermatitis disease severity. 2. Compared to in-person visits, the online care model will result in similar improvements in quality of life. 3. Providers and subjects in the online group will achieve a similar level of overall satisfaction as those in the in-person group.

NCT ID: NCT00980629 Completed - Atopic Dermatitis Clinical Trials

Dose-Finding Study of M516102 in the Treatment of Pruritus Associated With Atopic Dermatitis

Start date: August 2008
Phase: Phase 2
Study type: Interventional

This study is to investigate the efficacy and safety of M516102 and to evaluate the dose response relationship of M516102 and placebo, in the treatment of pruritus associated with atopic dermatitis.