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Dermatitis, Atopic clinical trials

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NCT ID: NCT00985894 Completed - Atopic Dermatitis Clinical Trials

Comparison Between Asynchronous Online Care Model With Usual In Office Care for the Management of Atopic Dermatitis

Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if an asynchronous online model of teledermatology can achieve similar clinical outcomes as compared to conventional in-office care for the management of atopic dermatitis. The investigators also aim to determine the effects of this online care model on patient quality of life as well as patient and physician satisfaction. The investigators' hypotheses include the following: 1. Compared to in-person visits, the online care model will result in similar clinical improvement in atopic dermatitis disease severity. 2. Compared to in-person visits, the online care model will result in similar improvements in quality of life. 3. Providers and subjects in the online group will achieve a similar level of overall satisfaction as those in the in-person group.

NCT ID: NCT00980629 Completed - Atopic Dermatitis Clinical Trials

Dose-Finding Study of M516102 in the Treatment of Pruritus Associated With Atopic Dermatitis

Start date: August 2008
Phase: Phase 2
Study type: Interventional

This study is to investigate the efficacy and safety of M516102 and to evaluate the dose response relationship of M516102 and placebo, in the treatment of pruritus associated with atopic dermatitis.

NCT ID: NCT00980135 Completed - Atopic Dermatitis Clinical Trials

Sinecort Pilot Efficacy Study

Sinecort Pilot
Start date: November 2009
Phase: Phase 2
Study type: Interventional

The study shall prove whether treatment of atopic dermatitis is equally effective with Sinecort cream as compared to standard therapy (Hydrocortisone cream).

NCT ID: NCT00958516 Completed - Atopic Dermatitis Clinical Trials

Assessment of the Phototoxic Potential of LEO 29102 Cream

Start date: September 2009
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to evaluate the phototoxic potential of a single application on healthy skin of LEO 29102 cream in different doses.

NCT ID: NCT00946478 Completed - Atopic Dermatitis Clinical Trials

Effect of Pimecrolimus Cream on Cathelicidin Levels in Subjects With Eczema

Start date: October 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of topical pimecrolimus on the immune system by assessing the levels of antimicrobial peptides in the skin of patients with eczema. It is hypothesized that pimecrolimus applied topically will repair the body's immune system in patients with eczema by increasing antimicrobial peptides.

NCT ID: NCT00944632 Completed - Atopic Dermatitis Clinical Trials

Dose Escalation of Different Concentrations of ZK 245186 in Atopic Dermatitis

Start date: July 15, 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of three concentrations of ZK 245186 ointment and vehicle on increasing body surface areas for the treatment of atopic dermatitis and to obtain dose-response information for the three concentrations.

NCT ID: NCT00932074 Completed - Atopic Dermatitis Clinical Trials

A Study to Determine the Safety, Tolerability and Efficacy of KP‑413 in Subjects With Atopic Dermatitis(AD)

Start date: July 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the safety, tolerability and efficacy of KP‑413 topical ointment compared with vehicle ointment in treating adult subjects with atopic dermatitis (AD).

NCT ID: NCT00931411 Terminated - Atopic Dermatitis Clinical Trials

Tolerance and Efficacy of Formulation 609580 20 Versus Formulation 609209 in Children With Atopic Dermatitis

Start date: January 2009
Phase: N/A
Study type: Interventional

Atopic dermatitis is one of the most frequent skin diseases. The disease is often worst during winter months when the skin is drier. Mild to moderate cases of atopic dermatitis are often controlled by a moisturizer alone. The use of moisturizers has been shown to have beneficial effects on atopic dermatitis. It can break the dry skin cycle by hydrating the upper layer of the skin which may prevent the recurrence of the disease and can reduce the use of cream or ointment medications such as corticosteroids. Formulation 609580 20 was developed to keep the moisturizing efficacy of formulation 609209 but to improve its tolerance and cosmetic acceptability (easier to apply, nicer texture, etc.). The new formulation contains the same quantity of shea butter and glycerin but in a different excipient (inactive substance) than the commercial product. In addition, vitamin B3 was added to see if it could help in reducing itching. The purpose of this study is to determine the safety and efficacy of two study products in children with atopic dermatitis. One of the study products (formulation 609580 20) is not commercially available (outside of clinical trials such as this one). The other study product (formulation 609209) has been approved in Canada and is currently available commercially under the trade name Lipikar Baume. For this study the child will be randomly assigned to one of the following two groups: - Group 1: 50 children will receive formulation 609209, the commercial formula for 42 days and will receive formulation 609580 20, the new formula, for 14 days. - Group 2: 50 children will receive formulation 609580 20, the new formula, for 42 days and will receive formulation 609209, the commercial formula, for 14 days.

NCT ID: NCT00931242 Completed - Atopic Dermatitis Clinical Trials

Study of Apremilast in Atopic or Contact Dermatitis

Start date: June 2009
Phase: Phase 2
Study type: Interventional

The objective of this study is to evaluate the efficacy of apremilast in patients with recalcitrant atopic or contact dermatitis.

NCT ID: NCT00927212 Terminated - Atopic Dermatitis Clinical Trials

Topical Application of AS101 for the Treatment of Atopic Dermatitis

Start date: June 2009
Phase: Phase 2
Study type: Interventional

Atopic Dermatitis is a chronic non contagious disease that causes itchy, inflamed skin. The purpose of this study is to evaluate the safety and efficacy of topical AS101 ointment for the treatment of Atopic dermatitis.