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Denture Stomatitis clinical trials

View clinical trials related to Denture Stomatitis.

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NCT ID: NCT06395116 Active, not recruiting - Clinical trials for Inflammatory Response

Microbial Adhesion and Biofilm Formation on Denture Base Materials

Start date: January 20, 2023
Phase:
Study type: Observational

Polymethylmethacrylate (PMMA) has been the material of choice for fabricating complete dentures for more than 80 years now.(1,2) As a material it is easy to handle and can be easily repaired and polished. PMMA while being a low-cost material has good esthetics. Some disadvantages of PMMA as a material are surface roughness and porosities which lead to staining, plaque accumulation and bacterial adhesion over time. Among the various factors that can influence microbial attachment to surfaces, surface roughness, hydrophilicity and free surface energy of PMMA are most important. Carboxylate and methyl ester groups found in PMMA make it a very hydrophilic material with a large amount of free surface energy. Despite the influence of the chemical composition, processing methods play the most important role in developing surface roughness.

NCT ID: NCT06021847 Completed - Denture Stomatitis Clinical Trials

Ozonated Water in Treatment of Denture Stomatitis

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The effect of Ozonated water on the treatment of oral stomatitis associated with complete denture wearer in comparison to Chlorhexidine mouthwash

NCT ID: NCT05466305 Not yet recruiting - Denture Stomatitis Clinical Trials

Assessment of Maxillary Acrylic Resin Complete Dentures Reinforced by Gold Plated Cr-Co Palatal Plate

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Gold is widely used in prosthetics. Its use ranges from being employed in the fabrication of removable dentures, where the inner surface permanently touching oral cavity tissues, through to fixed dentures, and even some structures of certain implantological systems. All such items can be made of galvanized gold. Thus, new technologies have made gold and its alloys a kind of a universal material.

NCT ID: NCT03666195 Not yet recruiting - Denture Stomatitis Clinical Trials

The Anti-microbial Effect of Titanium Dioxide Nano Particles in Complete Dentures Made for Edentulous Patients

Start date: October 15, 2018
Phase: N/A
Study type: Interventional

Although cleaning dentures by immersion in chemical denture cleaning solutions is effective in reducing the number of bacteria, a large number remains adhering to the denture surface. Thus, the mechanical cleansing of dentures is imperative to remove adherent microbes, and prevent diseases. This is not always easy to achieve, due to un-compliant patients, or patients with diminished manual dexterity (e.g. Mani phalanx dysfunction or Rheumatoid Arthritis) that often require assistance in cleaning their dentures, which may not always be available. Therefore, the modification of denture base materials to provide them with antibacterial properties to control oral biofilm formation, and producing dentures that can be cleaned by simply rinsing in water would prove to be valuable in oral hygienic management in complete denture-wearing patients.

NCT ID: NCT02950623 Not yet recruiting - Denture Stomatitis Clinical Trials

Microbiological Study on Maxillary Complete Dentures of Two Different Materials

Start date: October 2016
Phase: N/A
Study type: Interventional

Cross over design the investigator divide participants to two groups group (A) will receive rapid heat cured denture base material and group (b) will receive the acrylic denture modified by titanium dioxide nanoparticles and after washout period alternatively group (a) will receive the acrylic denture modified by titanium dioxide nanoparticles AND group (b) will receive rapid heat cured denture base material the investigator will take swaps from dentures to count the anaerobic bacteria.

NCT ID: NCT02950584 Not yet recruiting - Denture Stomatitis Clinical Trials

Surface Roughness of Heat Cured Acrylic Resin Versus Acrylic Resin With Titanium Dioxide

Start date: October 2016
Phase: Phase 1
Study type: Interventional

Measurement of surface roughness of tow different material of denture base to find out which material is more hygienic by decreasing the amount of bacterial accumulation.

NCT ID: NCT02834832 Completed - Denture Stomatitis Clinical Trials

Novel Coating to Minimize Bacterial Adhesions and Tooth Wear in Denture Acrylic

Start date: November 2016
Phase:
Study type: Observational

This study evaluates the effect of coatings on bacterial adhesion on denture acrylic and the wear of denture teeth.

NCT ID: NCT02686632 Completed - Denture Stomatitis Clinical Trials

The Effectiveness of Palatal Brushing on Denture Stomatitis

Start date: September 2016
Phase: N/A
Study type: Interventional

Denture stomatitis (DS) is an oral biofilm associated inflammatory disease of the palatal mucosa. It is the most prevalent oral disease and the main indicator of poor oral health among denture wearers, affecting one-third of all complete denture wearers. The etiology of DS is multifactorial, with documented role of mechanical trauma, bacteria and fungi. Risk factors may include, poor oral hygiene and nocturnal use of dentures. However, the evidence is ambiguous, inconclusive and recurrence following routine antifungal therapy is common. The proposed study is a phase II clinical trial to evaluate the efficacy of palatal brushing in reducing the colony forming unit (CFU) count and clinical inflammation. The assessment of change in CFU count and clinical inflammation will be carried out at baseline, 3 months and 6 months.

NCT ID: NCT02201745 Completed - Dental Plaque Clinical Trials

Palatal Brushing for Denture Stomatitis

Start date: June 2012
Phase: N/A
Study type: Interventional

Several dental professionals recommend that complete denture wearers should brush their palate. Some advantages include better cleansing and blood flow, which may help to prevent or treat oral infections, such as denture-related stomatitis. However, there is no previous clinical trial dealing on that subject. Therefore, our goal is to evaluate whether palatal brushing may change the severity of denture stomatitis or counts of microbes on dentures and mucosa. After an initial exam and data collection, participants will receive instructions for palatal hygiene and will be assessed following 1 and 3 months. Collected data include patient-reported information, intraoral photographs and swabbing (for counting microbes). Tested Hypotheses: - There is no difference in the extent of palatal inflammation in edentulous patients with denture stomatitis before and after 3 months of palatal brushing. - There is no difference in the number of colony forming unit (CFU) of Candida isolated from palate and denture of patients affected by denture stomatitis before and after 3 months of palatal brushing.

NCT ID: NCT02166450 Recruiting - Denture Stomatitis Clinical Trials

Effects of Denture-Related Stomatitis on Blood Pressure in Denture Wearers

Start date: October 2011
Phase: N/A
Study type: Observational

The aim of this study is to evaluate the influence of presence of oral fungal infection, which leads to denture-related stomatitis, on blood pressure, endothelial function and immune cell phenotype in patients wearing dentures.