Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT02018783
Other study ID # dessensibilizantes
Secondary ID
Status Completed
Phase N/A
First received December 7, 2013
Last updated December 17, 2013
Start date April 2013
Est. completion date August 2013

Study information

Verified date December 2013
Source Federal University of São Paulo
Contact n/a
Is FDA regulated No
Health authority Brazil: Ethics Committee
Study type Interventional

Clinical Trial Summary

The aim of this study was to evaluate the efficacy of three desensitizing toothpastes for immediate and intermediate-term relief of CDH, when compared with a control toothpaste. One hundred and thirty-eight hypersensitive teeth were diagnosed and randomized into four groups according to the therapeutic agent of each desensitizing cream tested: 1) strontium acetate and calcium carbonate, 2) calcium carbonate and arginine 8%, 3) calcium phosphate nanoparticles and 4) a control toothpaste. The desensitizing creams were applied according to the manufacturer's instructions. Cervical dentin hypersensitivity was assessed at baseline, immediately, 24 hours and 30 days after the treatment. Cold and evaporative tests were used to assess the sensitivity level.


Recruitment information / eligibility

Status Completed
Enrollment 138
Est. completion date August 2013
Est. primary completion date August 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 22 Years to 48 Years
Eligibility Inclusion Criteria:

- subjects 18 years or older

- in good general and oral health; have complaint of CDH in teeth distributed in all 4 quadrants

- not making use of desensitizing agents

- not having undergone periodontal treatment over the past 3 months

- respond to evaporative stimulus with a score = 1.5 cm on VAS

Exclusion Criteria:

- patients who presented restorations and caries near the exposed dentin of the hypersensitive teeth

- who made frequent use of painkillers, anti-inflammatory and antidepressants drugs

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment


Intervention

Procedure:
Colgate
Slow-speed handpiece with a Robson brush for 3 seconds by repeating the procedure
Sensodyne
Digital application for 60 seconds.
Nano P
Slow-speed handpiece with a Robson brush for 10 seconds
Cocorico
Digital application for 60 seconds

Locations

Country Name City State
Brazil Periodontics Clinic, Department of Dentistry Diamantina Minas Gerais

Sponsors (1)

Lead Sponsor Collaborator
Federal University of São Paulo

Country where clinical trial is conducted

Brazil, 

Outcome

Type Measure Description Time frame Safety issue
Primary cervical dentin hypersensitivity The cervical dentin hypersensitivity was evaluated by an air blast (evaporative stimulus) for 5 seconds, and by a tetrafluoroethane spray (cold stimulus) for 5 seconds. 30 days Yes
See also
  Status Clinical Trial Phase
Completed NCT01426360 - Instant and Lasting Relief Effects of Strontium Chloride/Potassium Nitrate Dentifrice on Dentin Hypersensitivity N/A
Completed NCT01115452 - Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity Phase 2
Completed NCT02931734 - Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment N/A
Recruiting NCT03177109 - Comparison of Different Desensitizers in Reducing Dentinal Hypersensitivity Phase 3
Completed NCT06197555 - Comparision of the Clinical Efficacy of Different Desensitizing Toothpastes N/A
Completed NCT01592864 - The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity Phase 3
Completed NCT01724008 - The Efficacy of a Dentifrice in Providing Relief From Dentinal Hypersensitivity Phase 3
Recruiting NCT03076944 - Evaluation of Desensitization Protocols in Reduction of Dentin Hypersensitivity N/A
Recruiting NCT03083496 - Clinical Evaluation of Different Potassium Oxalate Concentrations in Dentin Hypersensitivity Treatment N/A
Completed NCT03072719 - The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity Phase 3
Completed NCT03515902 - The Effects of Mouthguard and Desensitizing Toothpaste in Reducing Dental Hypersensitivity N/A
Completed NCT04754763 - A Comparative Study On The Effect Of Propolis And Dentine Bonding Agent In Treating Dentine Hypersensitivity Early Phase 1
Completed NCT02929043 - Psychophysical Characterization and Brain Correlates of Dentine Hypersensitivity N/A
Completed NCT04005417 - Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity
Not yet recruiting NCT04179994 - Efficacy of Miswak Extract Toothpaste as Compared Potassium Nitrate in The Management of Dentinal Hypersensitivity N/A
Completed NCT01827670 - Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity Phase 3
Recruiting NCT05392868 - Managing Dentine Hypersensitivity With Silver Diamine Fluoride on Older Adults Phase 2
Completed NCT01075256 - Dose Response of a Tubule Occlusion Agent Phase 4
Completed NCT01691560 - Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity Phase 2
Completed NCT01592851 - Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity Phase 3