Dentin Sensitivity Clinical Trial
Official title:
Randomized Non-inferiority Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity
Subjects will be enrolled into 3 balanced groups each using a different strength toothpaste. Dental hypersensitivity (DHS) will be assessed at study start, midway and study end.
This study is a double-blind, randomized, placebo-and positive-controlled, stratified parallel group clinical trial. The three groups will be randomly assigned to use one of three test toothpastes having an identical base formulation but containing respectively either 0% nano-hydroxyapatite (HAP) (placebo), 15% nano-HAP or 5% KNO3 (positive control). All dental examinations for data collection will be conducted by the same Clinical Examiner. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02753075 -
A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.
|
N/A | |
Completed |
NCT06045026 -
A Real-World Evidence Study Evaluating Oral Health Related Quality Of Life With Use Of A Stannous Fluoride Anti-Sensitivity Toothpaste For Dentin Hypersensitivity Management
|
N/A | |
Completed |
NCT02861664 -
Assessment of the Efficacy of an Experimental Occlusion Technology Dentifrice in Dentinal Hypersensitivity
|
N/A | |
Completed |
NCT02542943 -
Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity
|
N/A | |
Completed |
NCT02226562 -
Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity
|
Phase 2 | |
Completed |
NCT02919202 -
Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
|
N/A | |
Not yet recruiting |
NCT04485299 -
Clinical Assessment of Bifluorid 10 vs Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient
|
Phase 2/Phase 3 | |
Completed |
NCT02931734 -
Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment
|
N/A | |
Completed |
NCT02923895 -
To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH)
|
Phase 4 | |
Withdrawn |
NCT03361774 -
A Clinical Method Development Study to Characterise The Efficacy of a Dentifrice For The Relief Of Dentin Hypersensitivity
|
Phase 2 | |
Completed |
NCT02924350 -
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (DH)
|
N/A | |
Completed |
NCT05083052 -
Propolis in Reducing Dentin Hypersensitivity
|
N/A | |
Active, not recruiting |
NCT06150573 -
A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching
|
N/A | |
Completed |
NCT02937623 -
To Evaluate the Efficacy of an Experimental Dissolvable Strip in Rapidly Relieving Dentinal Hypersensitivity (DH)
|
N/A | |
Completed |
NCT02612064 -
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
|
N/A | |
Completed |
NCT02293044 -
A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity
|
N/A | |
Completed |
NCT02128633 -
Effectiveness of a Homecare Dentin Hypersensitivity Gel
|
Phase 2/Phase 3 | |
Completed |
NCT03310268 -
A Clinical Study to Evaluate a Stannous Fluoride Toothpaste for the Relief of Dentinal Hypersensitivity
|
N/A | |
Completed |
NCT05750745 -
A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste for the Relief of Dentine Hypersensitivity in a Chinese Population
|
N/A | |
Not yet recruiting |
NCT06417580 -
Effect of Pregabalin Gel in Controlling Cervical Dentin Hypersensitivity
|
Phase 2 |