Study of Long-Acting Acetaminophen in Postoperative Dental Pain

Status Completed

Clinical Trial Summary

The purpose of the study is to evaluate the efficacy and safety of acetaminophen ER 1500 mg (two 750 mg tablets) over 10 to 12 hours in the dental pain model following third molar extraction(s) and to evaluate the pharmacokinetics of acetaminophen ER 1500 mg (two 750 mg tablets) in a sub-group of subjects.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01960114
Study type	Interventional
Source	Johnson & Johnson Consumer and Personal Products Worldwide
Contact
Status	Completed
Phase	Phase 2
Start date	October 2013
Completion date	April 2014

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT00954356` - Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction	Phase 2
Completed	`NCT00942448` - Evaluation of the Efficacy and Safety of Diclofenac HPBCD 25, 50 mg/ml in the Treatment of Post-surgical Pain Following Dental Surgery	Phase 3
Completed	`NCT00943098` - Evaluation of the Efficacy and Safety of Diclofenac HPBCD 75mg/ml in Treatment of Pain Following Dental Surgery	Phase 3
Completed	`NCT00985439` - Study of Diclofenac Capsules to Treat Dental Pain	Phase 2
Completed	`NCT02966067` - A Split Mouth Trial to Compare Microneedles vs. Standard Needles in Dental Anaesthetic Delivery	N/A
Completed	`NCT01229228` - Study of Naproxen Capsules to Treat Dental Pain	Phase 2
Completed	`NCT01177423` - Efficiency Evaluation of Intradiploic Intra-osseus Anesthesia Versus Inferior Alveolar Nerve Block	N/A
Completed	`NCT03328208` - Nonpharmacologic Reduction of Periprocedural Distress and Drug Use	N/A
Completed	`NCT05236101` - Validation of Child Drawing Hospital Scale (CD: H) and the Place of the Drawing in the Evaluation of Dental Anxiety	N/A
Completed	`NCT00542035` - A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction	Phase 2
Completed	`NCT04231955` - Comparison of Different Pain Rating Scales in Patients With Symptomatic Teeth	N/A
Completed	`NCT02096926` - Methodological Validation of Ibuprofen Verses Placebo for Post Operative Pain After Third Molar Extraction Surgery	Phase 4
Completed	`NCT05369936` - Pain Perception: on Relationships Between Dental Anxiety and Olfaction	N/A
Recruiting	`NCT05351099` - Dental Block for Pain Relief in ED Dental Pain Patients
Not yet recruiting	`NCT06269406` - A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in Adults	N/A
Recruiting	`NCT05443009` - Self-Reported Pain in Children Submitted to Single Infiltration of Articaine During Primary Molar Extraction	Phase 4
Terminated	`NCT02161354` - Safety and Efficacy Study of NTC-510 to Treat Pain Following Dental Surgery of Third Molars	Phase 2
Completed	`NCT04949126` - Self Medication in Odontology (AUDE)
Completed	`NCT03652818` - Dental Pain Study of Analgesics in Patients Undergoing Molar Removal	Phase 2
Withdrawn	`NCT05194449` - Nonpharmacologic Reduction of Periprocedural Pain and Anxiety in Dentistry	N/A