Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy — NOADB  

Dental Diseases Clinical Trial

Official title: Evaluation of the Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy Patients: a Longitudinal Observational Cohort Study

Status Recruiting

Clinical Trial Summary

Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral anticoagulants. The aim of the present study is to observe the possible difference in intra-operative and post-operative bleeding events for single dental extraction.

Clinical Trial Description

Many protocols of drug suspension for surgical procedure has been designed, since the introduction of anticoagulant or antiplatelet medications. Nowadays it is not certain if suspension could give more costs than benefits for the surgical procedure itself. With the recent development of the Direct Oral Anticoagulant it is still unclear whether these medications might bring more bleeding events in the intra-operative and post-operative phase after oral surgery procedure, equal to, or more than Oral Anticoagulant Therapy. The purpose of this study is to assess the degree of intra- and post-operative bleeding complication between direct oral anticoagulant therapy patients and Oral Anticoagulant Therapy patients. ;

Related Conditions & MeSH terms

• Anticoagulant-induced Bleeding
• Dental Diseases
• Hemorrhage
• Postoperative Hemorrhage
• Stomatognathic Diseases

• NCT number: NCT03124030
• Study type: Observational
• Source: University of Trieste
• Contact: Roberto Di Lenarda, Prof
• Phone: 0403992254
• Email: rdilenarda@units.it
• Status: Recruiting
• Phase: N/A
• Start date: August 2, 2016
• Completion date: November 15, 2018